XXII

Company Overview — What Does 22nd Century Group, Inc. Do?

22nd Century Group, Inc., an agricultural biotechnology company, focuses on tobacco harm reduction, reduced nicotine tobacco, and enhancing health and wellness through plant science for the life science and consumer products industries. It develops very low nicotine content tobacco and cigarette products under the VLN King and VLN Menthol King names; and SPECTRUM research cigarettes for use in independent clinical studies. The company has collaboration with Keygene N.V. to develop hemp/cannabis plants for exceptional cannabinoid profiles and other superior agronomic traits for medical, therapeutic, and agricultural uses, as well as other applications. 22nd Century Group, Inc. was founded in 1998 and is headquartered in Buffalo, New York. 22nd Century Group, Inc. (XXII) is classified as a micro-cap stock in the Consumer Staples sector, specifically within the Tobacco Products industry. The company is led by CEO James A. Mish and employs approximately 80 people, headquartered in CLARENCE,, New York. With a market capitalization of $1M, XXII is one of the notable companies in the Consumer Staples sector.

22nd Century Group, Inc. (XXII) Stock Rating — Reduce (April 2026)

As of April 2026, 22nd Century Group, Inc. receives a Reduce rating with a composite score of 39.8/100 and 2 out of 5 stars from the Blank Capital Research quantitative model.XXII ranks #3,060 out of 4,446 stocks in our coverage universe. Within the Consumer Staples sector, 22nd Century Group, Inc. ranks #127 of 180 stocks, placing it in the lower half of its Consumer Staples peers. The rating is generated by a multi-factor model that weighs quality (30%), momentum (25%), value (15%), investment (10%), stability (10%), and short interest (10%).

XXII Stock Price and 52-Week Range

22nd Century Group, Inc. (XXII) currently trades at $2.15. The stock gained $0.12 (5.7%) in the most recent trading session. The 52-week high for XXII is $11.37, which means the stock is currently trading -81.1% from its annual peak. The 52-week low is $0.43, putting the stock 396.5% above its annual trough. Recent trading volume was 0 shares, suggesting relatively thin trading activity.

Is XXII Overvalued or Undervalued? — Valuation Analysis

22nd Century Group, Inc. (XXII) carries a value factor score of 7/100 in the Blank Capital model, signaling premium valuation that prices in significant future growth. The trailing price-to-earnings ratio is 2.30x, compared to the Consumer Staples sector average of 33.11x — a discount of 93%. The price-to-book ratio stands at 0.10x, versus the sector average of 1.74x. The price-to-sales ratio is 0.08x, compared to 0.35x for the average Consumer Staples stock.

At current multiples, 22nd Century Group, Inc. trades at a premium to most Consumer Staples peers. This elevated valuation may be justified if the company can sustain above-average growth rates and profitability, but it also creates downside risk if earnings disappoint expectations.

22nd Century Group, Inc. Profitability — ROE, Margins, and Quality Score

22nd Century Group, Inc. (XXII) earns a quality factor score of 25/100, signaling below-average profitability metrics relative to the broader market. The return on equity (ROE) is -38.1%, compared to the Consumer Staples sector average of 7.7%, which is below typical expectations for high-quality companies. Return on assets (ROA) comes in at -22.2% versus the sector average of 3.1%.

On a margin basis, 22nd Century Group, Inc. reports gross margins of 39.2%, compared to 26.2% for the sector. The operating margin is -63.3% (sector: 2.9%). Net profit margin stands at -20.6%, versus 1.6% for the average Consumer Staples stock. Revenue growth is running at -49.5% on a trailing basis, compared to 3.1% for the sector. Profitability is below benchmark levels, which may reflect industry headwinds, elevated reinvestment, or structural challenges.

XXII Debt, Balance Sheet, and Financial Health

22nd Century Group, Inc. has a debt-to-equity ratio of 4.0%, compared to the Consumer Staples sector average of 72.0%. The low leverage indicates a conservative balance sheet with significant financial flexibility. The current ratio is 2.42x, indicating strong short-term liquidity. Total debt on the balance sheet is $708,000. Cash and equivalents stand at $5M.

XXII has a beta of 0.03, meaning it is less volatile than the S&P 500, making it a relatively defensive holding. The stability factor score for 22nd Century Group, Inc. is 28/100, suggesting elevated price swings that may be unsuitable for conservative portfolios.

22nd Century Group, Inc. Revenue and Earnings History — Quarterly Trend

In TTM 2026, 22nd Century Group, Inc. reported revenue of $20M and earnings per share (EPS) of $-52.87. Net income for the quarter was $-6M. Gross margin was 39.2%. Operating income came in at $-12M.

In FY 2025, 22nd Century Group, Inc. reported revenue of $18M and earnings per share (EPS) of $-52.87. Net income for the quarter was $-5M. Gross margin was 42.1%. Revenue grew -27.9% year-over-year compared to FY 2024. Operating income came in at $-12M.

In Q3 2025, 22nd Century Group, Inc. reported revenue of $4M and earnings per share (EPS) of $1.55. Net income for the quarter was $5M. Gross margin was 36.3%. Revenue grew -32.5% year-over-year compared to Q3 2024. Operating income came in at $-3M.

In Q2 2025, 22nd Century Group, Inc. reported revenue of $4M and earnings per share (EPS) of $-13.61. Net income for the quarter was $-3M. Gross margin was 29.9%. Revenue grew -48.6% year-over-year compared to Q2 2024. Operating income came in at $-3M.

Over the past 8 quarters, 22nd Century Group, Inc. has demonstrated a growth trajectory, with revenue expanding from $8M to $20M. Investors analyzing XXII stock should weigh these quarterly trends alongside the valuation and quality metrics discussed above.

XXII Dividend Yield and Income Analysis

22nd Century Group, Inc. (XXII) does not currently pay a dividend. This is common among smaller companies in the Tobacco Products industry that prefer to reinvest cash flows into business expansion rather than returning capital to shareholders. Income-focused investors looking for Consumer Staples dividend stocks may want to explore other Consumer Staples stocks or use the stock screener to filter by dividend yield.

XXII Momentum and Technical Analysis Profile

22nd Century Group, Inc. (XXII) has a momentum factor score of 72/100, indicating strong price momentum with the stock outperforming the majority of the market over recent periods. Stocks with high momentum scores have historically tended to continue their outperformance in the near term. The investment factor score is 39/100, which measures capital allocation efficiency and asset growth patterns. The short interest score of 69/100 reflects moderate short selling activity.

XXII vs Competitors — Consumer Staples Sector Ranking and Peer Comparison

Within the Consumer Staples sector, 22nd Century Group, Inc. (XXII) ranks #127 out of 180 stocks based on the Blank Capital composite score. This places XXII in the lower half of all Consumer Staples stocks in our coverage universe. Key competitors and sector peers include Ituran Location & Control Ltd. (ITRN) with a score of 60.3/100, DARLING INGREDIENTS INC. (DAR) with a score of 52.9/100, Bunge Global SA (BG) with a score of 53.0/100, SANFILIPPO JOHN B & SON INC (JBSS) with a score of 54.1/100, and Archer-Daniels-Midland Co (ADM) with a score of 52.2/100.

Comparing XXII against the S&P 500 benchmark is also instructive for understanding relative performance. Investors can view the full XXII vs S&P 500 (SPY) comparison to assess how 22nd Century Group, Inc. stacks up against the broader market across all factor dimensions.

XXII Next Earnings Date

No upcoming earnings date has been announced for 22nd Century Group, Inc. (XXII) at this time. Check the earnings calendar for the latest scheduling updates across all stocks in our coverage universe.

Should You Buy XXII? — Investment Thesis Summary

The quantitative profile for 22nd Century Group, Inc. suggests caution. The quality score of 25/100 flags below-average profitability. The value score of 7/100 indicates premium valuation. Price momentum is positive at 72/100, suggesting the trend favors buyers. High volatility (stability score 28/100) increases portfolio risk.

In summary, 22nd Century Group, Inc. (XXII) earns a Reduce rating with a composite score of 39.8/100 as of April 2026. The rating is derived from the Blank Capital Research methodology, which combines six factor dimensions into a single quantitative ranking. Investors should consider these quantitative signals alongside their own fundamental research, risk tolerance, and investment time horizon before making buy or sell decisions on XXII stock.

Related Resources for XXII Investors

Explore more research and tools: XXII vs S&P 500 comparison, top Consumer Staples stocks, stock screener, our methodology, quality factor explained, value factor explained, momentum factor explained. Compare XXII head-to-head with peers: XXII vs ITRN, XXII vs DAR, XXII vs BG.