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Verdict
Quantitative factor alignment verified for current market regime.
Quant Score
Rank
#2132
Positioning
Market Dominance
Services
Healthcare
$1.8B
Jonathan Violin
Viridian Therapeutics, Inc. develops treatments for patients suffering from serious diseases. It develops VRDN-001, a humanized monoclonal anti-IGF-1R antibody that is in Phase 1/2 clinical trial for the treatment of thyroid eye disease (TED) The company was founded in 2006 and is headquartered in Waltham, Massachusetts.
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X-AXIS: EV/EBITDA (LOWER = CHEAPER) | Y-AXIS: ROE (HIGHER = ELITE) | RED CIRCLE = VRDN ANALYSIS TARGET
| Stock | Rating | Score▼ | Quality | Value | Momentum | P/E | EV/EBITDA | ROE | ROA | Gross Mgn | Op Mgn | Net Mgn | Rev Growth | Div Yield | D/E | Mkt Cap | AUDIT |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
$YALA Yalla Group Ltd | 75 | 89 | 99 | 80 | - | - | 21.3% | 18.6% | 64.5% | 35.7% | 39.5% | 6.5% | 0.0% | 0.0x | $644M | VS | |
$GRVY GRAVITY Co., Ltd. | 75 | 82 | 96 | 71 | - | - | 15.4% | 12.6% | 38.7% | 17.1% | 17.0% | -39.7% | 0.0% | 0.0x | $439M | VS | |
$ISSC INNOVATIVE SOLUTIONS & SUPPORT INC | 73 | 81 | 88 | 94 | 25.0x | 14.1x | 28.1% | 16.8% | 48.1% | 23.8% | 18.5% | 78.6% | 0.0% | 37.0x | $220M | VS | |
$AER AerCap Holdings N.V. | 72 | 60 | 87 | 84 | - | - | 12.4% | 2.9% | 100.0% | 28.2% | 26.2% | 5.5% | 0.8% | 264.0x | $19.4B | VS | |
$HCSG HEALTHCARE SERVICES GROUP INC | 72 | 74 | 88 | 88 | 7.1x | 6.1x | 28.9% | 20.8% | 20.8% | 9.9% | 9.3% | 8.5% | 0.0% | 1.0x | $1.2B | VS | |
$LQDT LIQUIDITY SERVICES INC | 72 | 90 | 88 | 68 | 24.9x | 14.3x | 14.6% | 7.8% | 43.8% | 7.4% | 5.9% | 31.2% | 0.0% | 0.0x | $857M | VS | |
$TRTNpA Triton International Ltd | 71 | 70 | 89 | 70 | - | 1.7x | 18.0% | 4.6% | 97.3% | 52.2% | 32.7% | -3.4% | 0.0% | 271.0x | $8.0B | VS | |
$EDU New Oriental Education & Technology Group Inc. | 71 | 83 | 52 | 77 | - | - | 9.4% | 4.9% | 55.5% | 8.7% | 7.7% | 13.6% | 1.3% | 7.0x | $78.0B | VS | |
$NTES NetEase, Inc. | 71 | 88 | 93 | 68 | - | - | 22.1% | 15.6% | 62.5% | 28.1% | 28.7% | -1.0% | 2.8% | 9.0x | $56.6B | VS | |
$UTI UNIVERSAL TECHNICAL INSTITUTE INC | 70 | 86 | 86 | 72 | 43.2x | 16.0x | 21.4% | 8.0% | 100.0% | 10.0% | 7.5% | 14.1% | 0.0% | 27.0x | $1.8B | VS | |
$VRDN Viridian Therapeutics, Inc.\DE | 49 | 37 | 23 | 84 | - | - | -59.4% | -51.8% | 100.0% | -92463.0% | -86061.7% | 97913.9% | 0.0% | 15.0x | $1.8B | ||
| SECTOR BENCH | - | - | - | - | - | 23.7x | 11.7x | 5.3% | 1.9% | 59.6% | 3.5% | 2.3% | 7.8% | 0.0% | 0.3x | - | REF |
Viridian Therapeutics, Inc.\DE (VRDN) receives a "Reduce" rating with a composite score of 49.2/100. It ranks #2132 out of 7,333 stocks in our coverage universe and carries a 2-star rating. Ratings are driven by a 6-factor quantitative model measuring quality, value, momentum, investment, stability, and short interest.
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YOY expansion rate
Core pricing power
Operating efficiency
Bottom-line conversion
Equity capital efficiency
Asset base utilization
Financial leverage load
Direct cash return
Jonathan Violin
Chief Executive Officer
Labor Force
50
37
27
66
Audit Verdict: Lower quality and stability scores may indicate governance concerns.
No recent insider transactions available for VRDN
Outperforming peers — winners tend to keep winning over 3-12 months
Expensive relative to fundamentals — limited margin of safety
Average quality profile
Low volatility — smoother ride and historically better risk-adjusted returns
Aggressive spending — empire-building risk, dilutive growth
Mid-range overall rating
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Relative valuation derived from Services sector benchmarks. Model weights: EV/EBITDA (40%), P/B (35%), P/S (25%). Re-calculated daily.
No analyst ratings for VRDN.
View All RatingsMaterial decline in asset turnover efficiency detected
High margin volatility — erratic forensic earnings quality
| Factor | Global | Sector | Tilt |
|---|---|---|---|
| PROFITABILITY | 37 | 28 | +9ALPHA |
| MOMENTUM | 84 | 92 | -8DRAG |
| VALUATION | 23 | 14 | +9ALPHA |
| INVESTMENT | 27 | 22 | +5NEUTRAL |
| STABILITY | 66 | 72 | -6DRAG |
| SHORT INT | 41 | 35 | +6ALPHA |
Global = full universe. Sector = relative to industry peers. Positive tilt indicates idiosyncratic strength.
ROE proxy -59.4% (sector 5.3%)
GM 100% vs sector 60%, OM -92463% vs sector 4%
Capital turnover N/A
Rev growth 97914%, 10yr history
Interest coverage -71.5x
Composite assessment of profitability, capital efficiency, and financial strength. Top-tier entities demonstrate sustainable cash flow generation and elite competitive moats.
Profit generated per dollar of shareholder equity
Efficiency of asset utilization
Pricing power and cost efficiency
Core business profitability
Bottom-line profitability
The Quality factor evaluates the persistence and magnitude of realized cash flows. Companies with scores >70 exhibit superior pricing power and structural financial resilience through diverse economic regimes.
Our uncertainty rating tracks the predictability of future cash flows and potential for permanent capital loss. Moderate visibility with standard industry cyclicality.
Viridian Therapeutics, Inc.\DE receives a Reduce rating from our analysis, with a composite score of 49.2/100 and 2 out of 5 stars, ranking #2132 out of 7,333 stocks. VRDN's factor profile shows weakness across multiple dimensions, suggesting the stock may underperform going forward. Existing holders may want to consider trimming positions or tightening stop-losses.
VRDN's quality score of 37/100 is below average, suggesting challenges with profitability or capital efficiency. The company reports a return on equity of -59.4% (sector avg: 5.3%), gross margins of 100.0% (sector avg: 59.6%), net margins of -86061.7% (sector avg: 2.3%). Investors should examine whether management is actively addressing these weaknesses or if they reflect structural industry headwinds.
VRDN registers a value score of just 23/100, suggesting the stock trades at a significant premium to its fundamental metrics. Key valuation metrics include a P/B ratio of 5.21x. High-premium valuations like this require strong future execution to avoid multiple compression, and downside risk is elevated if growth disappoints.
Viridian Therapeutics, Inc.\DE's investment score of 27/100 suggests limited reinvestment activity. Key growth metrics include revenue growth of 97913.9% vs. a sector average of 7.8% and a return on assets of -51.8% (sector: 1.9%). While this can be positive for mature, cash-generative businesses returning capital to shareholders, it may also signal a lack of growth opportunities or management conservatism.
VRDN shows strong momentum characteristics with a score of 84/100. The stock has been trending above key moving averages, indicating solid demand from institutional buyers. Revenue growth stands at 97913.9% year-over-year, while a beta of 0.90 reflects its sensitivity to broader market moves. This level of momentum typically signals sustained investor confidence and favorable near-term price action.
VRDN shows good financial stability with a score of 66/100. Key stability metrics include a beta of 0.90 and a debt-to-equity ratio of 15.00x (sector avg: 0.3x). This suggests manageable leverage and moderate price volatility, making it appropriate for investors seeking a balance between growth potential and capital preservation.
The short interest score of 41/100 for VRDN suggests somewhat elevated bearish positioning by institutional traders. Specific risk factors include elevated leverage (D/E: 15.00x), small-cap liquidity risk. With a $1.8B market cap (small-cap), Viridian Therapeutics, Inc.\DE may experience above-average volatility. Investors should consider whether the short thesis has merit or if it creates a potential short-squeeze opportunity.
Viridian Therapeutics, Inc.\DE is a small-cap company in the Services sector, ranked #0 of 50 in its sector (100th percentile) and #2132 of 7,333 overall (71st percentile). Key comparisons include ROE of -59.4% trailing the 5.3% sector median and operating margins of -92463.0% below the 3.5% sector average. This top-quartile standing reflects exceptional competitive strength relative to Services peers.
While VRDN currently exhibits a REDUCE profile, superior opportunities exist within the SERVICES sector. Our model identifies several "Strong Buy" candidates with higher quality scores and more attractive valuations among direct industry competitors.
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Improvement in Value (23) would have the largest impact on the composite score.
ROE 1219% BELOW SECTOR MEDIAN
Gross Margin 68% ABOVE SECTOR MEDIAN (FAVORABLE)
Op. Margin 2634373% BELOW SECTOR MEDIAN
AUDIT DATA AS OF SEP 30, 2025 (Q2 FY2025)
We rate Viridian Therapeutics, Inc.\DE (VRDN) as a Reduce with a composite score of 49.2/100 at a current price of $29.39. The quantitative profile shows weakness across multiple dimensions, suggesting limited upside potential and elevated risk of underperformance relative to peers over the next 12 months.
The rating is primarily driven by strength in momentum (84th percentile) and stability (66th percentile), which together account for the majority of the composite score. Offsetting weakness in value (23th percentile) and investment (27th percentile) tempers our overall conviction. We assign a No Moat rating (25/100), Medium uncertainty, and Poor capital allocation.
Key items to watch: sustainability of the current growth rate; the path to profitability; valuation compression risk if growth disappoints. Any material change in these dynamics could warrant a reassessment of our rating. The moat trend is stable, which suggests the competitive landscape is stable for now.
Viridian Therapeutics, Inc.\DE holds a top-quartile position (#0 of 50) within the Services sector, based on our composite quantitative scoring across quality, value, momentum, and stability factors. The composite score of 49.2/100 places it at rank #2132 in our full 7,333-stock universe. At $1.8B in market capitalization, Viridian Therapeutics, Inc.\DE is a small-cap player in the Services space, which limits certain scale advantages but may allow for more agile strategic execution.
The near-term outlook is constructive, with revenue growing at 97914% and momentum in the 84th percentile confirming positive market sentiment and institutional accumulation. The combination of strong top-line growth and favorable price dynamics suggests the company is executing well on its growth strategy. Investment factor at the 27th percentile indicates reinvestment patterns that investors should monitor for sustainability.
The margin cascade tells an important story: gross margins of 100% (+40.4pp vs sector) narrow to operating margins of -92463% (-92466.5pp vs sector) and net margins of -86061.7%, yielding a gross-to-net conversion rate of -86062%. The significant margin erosion from gross to net suggests elevated operating expenses, high interest costs, or other structural drags that warrant monitoring.
At a current price of $29.39, Viridian Therapeutics, Inc.\DE is trading at a premium to fundamental value. Our value factor score of 23/100 reflects a composite assessment across multiple valuation metrics including price-to-earnings, price-to-book, EV/EBITDA, and price-to-sales ratios relative to both sector peers and the broader market. The premium valuation implies the market is pricing in significant future growth or quality improvements that are not yet fully reflected in current fundamentals.
The stock currently trades at P/B of 5.2x, P/S of 37.0x. We evaluate these multiples in the context of both absolute levels and sector-relative positioning to form our valuation view.
Gross margins of 100% signal strong pricing power and brand/IP advantages — businesses with margins above 40% have historically demonstrated more resilient earnings through economic cycles.
Revenue growth of 97914% confirms the business is expanding its addressable market — growth at this level typically supports multiple expansion and attracts institutional capital.
A conservative balance sheet (15% D/E) provides financial flexibility for acquisitions, buybacks, or weathering economic downturns without dilution.
Positive momentum (84th percentile) indicates institutional accumulation and favorable technical dynamics that tend to persist in the intermediate term.
The Reduce rating (composite 49.2/100) reflects multi-factor weakness, and historically, stocks in this scoring range have underperformed the market by a meaningful margin.
We assign a Medium uncertainty rating to Viridian Therapeutics, Inc.\DE. The stock presents a balanced risk profile: current negative profitability (net margin -86061.7%). While not risk-free, the core business fundamentals are adequate to withstand moderate economic stress, and the range of potential outcomes around our fair value estimate is manageable.
Specific risk factors that inform our assessment include: current negative profitability (net margin -86061.7%). Each of these factors independently widens the distribution of potential outcomes, and in combination they create a risk profile that demands careful position sizing. The stability factor at the 66th percentile and quality factor at the 37th percentile provide a quantitative summary of the overall risk landscape.
Key risk mitigants include: healthy gross margins of 100% provide a buffer against cost pressures; conservative leverage (15% D/E) limits balance sheet risk; above-average stability (66th percentile) suggests predictable business dynamics. These factors partially offset the identified risks and provide downside protection in adverse scenarios. On balance, the risk-reward profile is favorable for long-term investors.
We rate Viridian Therapeutics, Inc.\DE's capital allocation as Poor. Key concerns include low returns on equity (-59.4%), negative profitability, weak asset returns (ROA -51.8%). Exemplary capital allocators generate ROE above 20% and maintain conservative leverage — Viridian Therapeutics, Inc.\DE significantly underperforms these benchmarks, raising questions about management's ability to create shareholder value.
Investors should scrutinize management's reinvestment decisions and balance sheet trajectory before committing capital. Poor capital allocation often compounds over time: overlevered balance sheets limit strategic flexibility, while low returns on capital destroy shareholder value. We would need to see sustained improvement in profitability metrics and balance sheet discipline before considering an upgrade.
In summary, Viridian Therapeutics, Inc.\DE receives a Reduce rating with a composite score of 49.2/100 (rank #2132 of 7,333). Our quantitative framework assigns a No Moat (25/100, trend: stable), Medium uncertainty, and Poor capital allocation. The average factor score across quality, value, momentum, stability, and investment is 47/100.
Our analysis does not support a constructive view on Viridian Therapeutics, Inc.\DE at this time. The combination of limited competitive advantages, medium uncertainty, and poor capital allocation suggests unfavorable risk-reward at current levels. We recommend investors avoid new positions and existing holders consider reducing exposure.
Analysis derived from Blank Capital Research quantitative terminal. For informational purposes only. No trade solicitation. Past performance not indicative of future results. Consult a qualified advisor.
We do not assign Viridian Therapeutics, Inc.\DE a meaningful economic moat, scoring 25/100 on our composite assessment. Current fundamentals do not demonstrate the kind of durable competitive advantages — such as superior returns on invested capital, margin superiority, or reinvestment efficiency — that would protect the company from competitive erosion over the long term. The highest-scoring pillar, growth durability, reached only 9.5/20.
The strongest moat sources are growth durability (9.5/20) and margin superiority (9.2/20). Rev growth 97914%, 10yr history. GM 100% vs sector 60%, OM -92463% vs sector 4%. These pillars form the core of Viridian Therapeutics, Inc.\DE's competitive identity and are the primary drivers of excess returns in our framework.
Areas of relative weakness include economic value creation (0/20) and reinvestment efficiency (0/20). ROE proxy -59.4% (sector 5.3%). Improvement in these areas could meaningfully widen the moat over time, while deterioration would be an early warning of competitive erosion.
Our moat trend assessment is Stable. Multi-year ROIC and operating margin trajectories show neither meaningful improvement nor deterioration, suggesting the competitive position is steady. We expect Viridian Therapeutics, Inc.\DE's moat profile to remain largely unchanged absent a material shift in return on capital or industry dynamics.
Key profit drivers include gross margins of 100% providing a solid profitability foundation, robust top-line growth of 97914% expanding the revenue base. The margin cascade from 100% gross to -92463% operating to -86061.7% net reveals the company's cost structure and reinvestment intensity. Our analysis indicates that profit quality raises some durability concerns, with the quality factor at the 37th percentile.
The margin profile shows gross margins of 100%, operating margins of -92463%, net margins of -86061.7%. Return metrics include ROE of -59.4% and ROA of -51.8%. Relative to the Services sector, gross margins are 40.4 percentage points above the sector median of 60%, and ROE of -59.4% compares to a sector median of 5.3%.
The balance sheet reflects a conservatively managed balance sheet with D/E of 15%, revenue growth of 97914%. The sector median D/E is 0%, putting Viridian Therapeutics, Inc.\DE at higher leverage than the typical peer. Overall balance sheet health is adequate for the current business environment.
Thin net margins of -86061.7% provide limited cushion against cost pressures, competitive pricing, or macroeconomic headwinds — even small changes in costs could swing the company to a loss.
Above 50MA
37.18%
Net New Highs
+51081

The biotech sector rebounded strongly in 2025 as M&A activity surged, becoming a stabilizing force for small and mid-cap companies. With 57% of biopharma acquisitions involving smaller firms and $30.9 billion in deals, investor sentiment shifted from GLP-1 drugs toward cancer and autoimmune disease treatments, particularly next-generation CAR-T therapies. Looking ahead to 2026, analysts expect continued M&A activity and strategic partnerships, though risks remain including FDA staff turnover and an 'IPO air pocket' from the 2023-2024 downturn.

7 analysts have expressed a variety of opinions on Viridian Therapeutics (NASDAQ:VRDN) over the past quarter, offering a diverse set of opinions from bullish to bearish. In the table below, you'll find a summary of their recent ratings, revealing the shifting sentiments over the past 30 days and comparing them to the previous months. Bullish Somewhat Bullish Indifferent Somewhat Bearish Bearish Total Ratings 5 1 1 0 0 Last 30D 1 0 0 0 0 1M Ago 2 1 1 0 0 2M Ago 0 0 0 0 0 3M Ago 2 0 0 0 0 In the assessment of 12-month price targets, analysts unveil insights for Viridian Therapeutics, presenting an average target of $26.57, a high estimate of $31.00, and a low estimate of $20.00. A decline of 15.38% from the prior average price target is evident in the current average. Understanding Analyst Ratings: A Comprehensive Breakdown The standing of Viridian Therapeutics among financial experts becomes clear with a thorough analysis of recent analyst actions. The summary below outlines key analysts, their recent evaluations, and adjustments to ratings and price targets. Analyst Analyst Firm Action Taken Rating Current Price Target Prior Price Target Richard Law Goldman Sachs Announces Buy $23.00 - Douglas Tsao HC Wainwright & Co. Lowers Buy $27.00 $37.00 Leland Gershell Oppenheimer Lowers Outperform $31.00 $36.00 Kalpit Patel B. Riley Securities Lowers Neutral $20.00 $25.00 Serge Belanger Needham Maintains Buy $30.00 - Kalpit Patel B. Riley Securities Lowers Buy $25.00 $29.00 Serge Belanger Needham Maintains Buy $30.00 $30.00 Key Insights: Action Taken: Analysts respond to changes in market conditions and company performance, frequently updating ...Full story available on Benzinga.com

Viridian Therapeutics reported Q2 2025 results, highlighting progress in thyroid eye disease treatment with veligrotug, securing FDA Breakthrough Therapy Designation and a $70 million licensing deal with Kissei Pharmaceutical, while experiencing increased research expenses and net losses.
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