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Verdict
Quantitative factor alignment verified for current market regime.
Quant Score
Rank
#2413
Positioning
Market Dominance
Services
Healthcare
$9.0B
David D. Halbert
We are a leading, patient-centric, next-generation AI TechBio company and precision medicine pioneer. We develop and commercialize innovative solutions to transform healthcare through the use of comprehensive molecular information and artificial intelligence/machine learning algorithms at scale. Our principal executive offices are located in Irving, Texas.
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X-AXIS: EV/EBITDA (LOWER = CHEAPER) | Y-AXIS: ROE (HIGHER = ELITE) | RED CIRCLE = CAI ANALYSIS TARGET
| Stock | Rating | Score▼ | Quality | Value | Momentum | P/E | EV/EBITDA | ROE | ROA | Gross Mgn | Op Mgn | Net Mgn | Rev Growth | Div Yield | D/E | Mkt Cap | AUDIT |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
$YALA Yalla Group Ltd | 75 | 89 | 99 | 80 | - | - | 21.3% | 18.6% | 64.5% | 35.7% | 39.5% | 6.5% | 0.0% | 0.0x | $644M | VS | |
$GRVY GRAVITY Co., Ltd. | 75 | 82 | 96 | 71 | - | - | 15.4% | 12.6% | 38.7% | 17.1% | 17.0% | -39.7% | 0.0% | 0.0x | $439M | VS | |
$ISSC INNOVATIVE SOLUTIONS & SUPPORT INC | 73 | 81 | 88 | 94 | 25.0x | 14.1x | 28.1% | 16.8% | 48.1% | 23.8% | 18.5% | 78.6% | 0.0% | 37.0x | $220M | VS | |
$AER AerCap Holdings N.V. | 72 | 60 | 87 | 84 | - | - | 12.4% | 2.9% | 100.0% | 28.2% | 26.2% | 5.5% | 0.8% | 264.0x | $19.4B | VS | |
$HCSG HEALTHCARE SERVICES GROUP INC | 72 | 74 | 88 | 88 | 7.1x | 6.1x | 28.9% | 20.8% | 20.8% | 9.9% | 9.3% | 8.5% | 0.0% | 1.0x | $1.2B | VS | |
$LQDT LIQUIDITY SERVICES INC | 72 | 90 | 88 | 68 | 24.9x | 14.3x | 14.6% | 7.8% | 43.8% | 7.4% | 5.9% | 31.2% | 0.0% | 0.0x | $857M | VS | |
$TRTNpA Triton International Ltd | 71 | 70 | 89 | 70 | - | 1.7x | 18.0% | 4.6% | 97.3% | 52.2% | 32.7% | -3.4% | 0.0% | 271.0x | $8.0B | VS | |
$EDU New Oriental Education & Technology Group Inc. | 71 | 83 | 52 | 77 | - | - | 9.4% | 4.9% | 55.5% | 8.7% | 7.7% | 13.6% | 1.3% | 7.0x | $78.0B | VS | |
$NTES NetEase, Inc. | 71 | 88 | 93 | 68 | - | - | 22.1% | 15.6% | 62.5% | 28.1% | 28.7% | -1.0% | 2.8% | 9.0x | $56.6B | VS | |
$UTI UNIVERSAL TECHNICAL INSTITUTE INC | 70 | 86 | 86 | 72 | 43.2x | 16.0x | 21.4% | 8.0% | 100.0% | 10.0% | 7.5% | 14.1% | 0.0% | 27.0x | $1.8B | VS | |
$CAI Caris Life Sciences, Inc. | 48 | 67 | 45 | 27 | 196.0x | 45.1x | 20.3% | 9.9% | 68.0% | 15.0% | 11.2% | 113.4% | 0.0% | 79.0x | $9.0B | ||
| SECTOR BENCH | - | - | - | - | - | 23.7x | 11.7x | 5.3% | 1.9% | 59.6% | 3.5% | 2.3% | 7.8% | 0.0% | 0.3x | - | REF |
Caris Life Sciences, Inc. (CAI) receives a "Reduce" rating with a composite score of 47.5/100. It ranks #2413 out of 7,333 stocks in our coverage universe and carries a 2-star rating. Ratings are driven by a 6-factor quantitative model measuring quality, value, momentum, investment, stability, and short interest.
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YOY expansion rate
Core pricing power
Operating efficiency
Bottom-line conversion
Equity capital efficiency
Asset base utilization
Financial leverage load
Direct cash return
David D. Halbert
Chief Executive Officer
Labor Force
1,769
67
26
53
Audit Verdict: Lower quality and stability scores may indicate governance concerns.
No recent insider transactions available for CAI
Lagging peers — losers tend to keep underperforming
Fair valuation relative to peers
High profitability & efficiency — strong quality floor supports entry
Average volatility — neutral timing signal
Aggressive spending — empire-building risk, dilutive growth
Mid-range overall rating
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Relative valuation derived from Services sector benchmarks. Model weights: EV/EBITDA (40%), P/B (35%), P/S (25%). Re-calculated daily.
Projection based on user-defined inputs. Re-calculated daily against current market data.
Reverse DCF Framework — Mauboussin Methodology
Institutional-grade Reverse DCF analysis. This model identifies the growth hurdles embedded in current market prices. When implied growth is significantly lower than historical or projected rates, a margin of safety may exist. Re-audited daily.
No analyst ratings for CAI.
View All RatingsInsufficient data for Financial Analysis
| Factor | Global | Sector | Tilt |
|---|---|---|---|
| PROFITABILITY | 67 | 82 | -15DRAG |
| MOMENTUM | 27 | 20 | +7ALPHA |
| VALUATION | 45 | 44 | +1NEUTRAL |
| INVESTMENT | 26 | 17 | +9ALPHA |
| STABILITY | 53 | 56 | -3NEUTRAL |
| SHORT INT | 74 | 88 | -14DRAG |
Global = full universe. Sector = relative to industry peers. Positive tilt indicates idiosyncratic strength.
ROE proxy 20.3% (sector 5.3%)
GM 68% vs sector 60%, OM 15% vs sector 4%
Capital turnover N/A, R&D intensity 11.7%
Rev growth 113%
Interest coverage 2.4x, Net debt/EBITDA -11.6x
Composite assessment of profitability, capital efficiency, and financial strength. Top-tier entities demonstrate sustainable cash flow generation and elite competitive moats.
Profit generated per dollar of shareholder equity
Efficiency of asset utilization
Pricing power and cost efficiency
Core business profitability
Bottom-line profitability
The Quality factor evaluates the persistence and magnitude of realized cash flows. Companies with scores >70 exhibit superior pricing power and structural financial resilience through diverse economic regimes.
Our uncertainty rating tracks the predictability of future cash flows and potential for permanent capital loss. Moderate visibility with standard industry cyclicality.
Caris Life Sciences, Inc. receives a Reduce rating from our analysis, with a composite score of 47.5/100 and 2 out of 5 stars, ranking #2413 out of 7,333 stocks. CAI's factor profile shows weakness across multiple dimensions, suggesting the stock may underperform going forward. Existing holders may want to consider trimming positions or tightening stop-losses.
CAI earns a quality score of 67/100, indicating above-average business quality. The company reports a return on equity of 20.3% (sector avg: 5.3%), gross margins of 68.0% (sector avg: 59.6%), net margins of 11.2% (sector avg: 2.3%). Companies in this tier generally demonstrate consistent profitability and efficient capital deployment, though they may face some competitive pressure.
With a value score of 45/100, CAI appears somewhat expensive relative to its fundamentals. Key valuation metrics include a P/E ratio of 196.00x, an EV/EBITDA of 45.08x, a P/B ratio of 11.52x. Investors paying a premium here are likely betting on above-average growth or margin expansion to justify current prices.
Caris Life Sciences, Inc.'s investment score of 26/100 suggests limited reinvestment activity. Key growth metrics include revenue growth of 113.4% vs. a sector average of 7.8% and a return on assets of 9.9% (sector: 1.9%). While this can be positive for mature, cash-generative businesses returning capital to shareholders, it may also signal a lack of growth opportunities or management conservatism.
Caris Life Sciences, Inc. is experiencing notably weak momentum with a score of just 27/100. The stock has underperformed its peers and is trending below major moving averages. Revenue growth stands at 113.4% year-over-year, while a beta of 1.19 reflects its sensitivity to broader market moves. While deep momentum weakness can occasionally present value opportunities, it often reflects deteriorating fundamentals or structural headwinds that may persist.
With a stability score of 53/100, CAI exhibits average financial resilience. Key stability metrics include a beta of 1.19 and a debt-to-equity ratio of 79.00x (sector avg: 0.3x). While the balance sheet is not a major concern, the stock is subject to typical market volatility and may experience sharper drawdowns during risk-off episodes.
CAI carries a short interest score of 74/100, indicating moderate short selling activity. This is a neutral reading — not enough to signal systemic bearishness, but worth monitoring. Specific risk factors include elevated leverage (D/E: 79.00x). At $9.0B market cap (mid-cap), Caris Life Sciences, Inc. offers reasonable institutional liquidity.
Caris Life Sciences, Inc. is a mid-cap company in the Services sector, ranked #0 of 50 in its sector (100th percentile) and #2413 of 7,333 overall (67th percentile). Key comparisons include ROE of 20.3% exceeding the 5.3% sector median and operating margins of 15.0% above the 3.5% sector average. This top-quartile standing reflects exceptional competitive strength relative to Services peers.
While CAI currently exhibits a REDUCE profile, superior opportunities exist within the SERVICES sector. Our model identifies several "Strong Buy" candidates with higher quality scores and more attractive valuations among direct industry competitors.
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Improvement in Investment (26) would have the largest impact on the composite score.
EV/EBITDA 284% ABOVE SECTOR MEDIAN
ROE 283% ABOVE SECTOR MEDIAN (FAVORABLE)
Gross Margin 14% ABOVE SECTOR MEDIAN (FAVORABLE)
AUDIT DATA AS OF SEP 30, 2025 (Q2 FY2025)
We rate Caris Life Sciences, Inc. (CAI) as a Reduce with a composite score of 47.5/100 at a current price of $18.20. The quantitative profile shows weakness across multiple dimensions, suggesting limited upside potential and elevated risk of underperformance relative to peers over the next 12 months.
The rating is primarily driven by strength in quality (67th percentile) and stability (53th percentile), which together account for the majority of the composite score. Offsetting weakness in investment (26th percentile) and momentum (27th percentile) tempers our overall conviction. We assign a Narrow Moat rating (53/100), Medium uncertainty, and Standard capital allocation.
Key items to watch: momentum to confirm whether the current price trend has legs; sustainability of the current growth rate. Any material change in these dynamics could warrant a reassessment of our rating. The moat trend is stable, which suggests the competitive landscape is stable for now.
Caris Life Sciences, Inc. holds a top-quartile position (#0 of 50) within the Services sector, based on our composite quantitative scoring across quality, value, momentum, and stability factors. The composite score of 47.5/100 places it at rank #2413 in our full 7,333-stock universe. At $9.0B in market capitalization, Caris Life Sciences, Inc. is a mid-cap player in the Services space, which limits certain scale advantages but may allow for more agile strategic execution.
Revenue is growing at 113%, though momentum at the 27th percentile suggests the market has not yet fully recognized this trajectory. This potential disconnect between fundamental improvement and market recognition could represent an opportunity for patient investors if the growth trend persists.
The margin cascade tells an important story: gross margins of 68% (+8.4pp vs sector) narrow to operating margins of 15% (+11.5pp vs sector) and net margins of 11.2%, yielding a gross-to-net conversion rate of 16%. This conversion rate is typical for the sector, suggesting a standard cost structure without notable efficiency advantages or disadvantages.
At a current price of $18.20, Caris Life Sciences, Inc. is trading near fair value based on current fundamentals. Our value factor score of 45/100 reflects a composite assessment across multiple valuation metrics including price-to-earnings, price-to-book, EV/EBITDA, and price-to-sales ratios relative to both sector peers and the broader market. Valuation metrics are mixed, with no strong signal of mispricing in either direction.
The stock currently trades at a P/E of 196.0x (a 726% premium to the sector median of 23.7x), EV/EBITDA of 45.1x (at a premium), P/B of 11.5x, P/S of 6.3x. The above-sector P/E multiple suggests the market is pricing in superior growth or quality, which our analysis partially supports given strong quality metrics.
Gross margins of 68% signal strong pricing power and brand/IP advantages — businesses with margins above 40% have historically demonstrated more resilient earnings through economic cycles.
Returns on equity of 20.3% exceed the cost of equity for most companies, indicating genuine shareholder value creation and a reinvestment engine that compounds wealth over time.
Revenue growth of 113% confirms the business is expanding its addressable market — growth at this level typically supports multiple expansion and attracts institutional capital.
Return on assets of 9.9% indicates efficient deployment of the full asset base, not just equity capital.
The Reduce rating (composite 47.5/100) reflects multi-factor weakness, and historically, stocks in this scoring range have underperformed the market by a meaningful margin.
We assign a Medium uncertainty rating to Caris Life Sciences, Inc.. The stock presents a balanced risk profile: elevated valuation multiple (P/E 196.0x) that leaves limited margin for error. While not risk-free, the core business fundamentals are adequate to withstand moderate economic stress, and the range of potential outcomes around our fair value estimate is manageable.
Specific risk factors that inform our assessment include: elevated valuation multiple (P/E 196.0x) that leaves limited margin for error. Each of these factors independently widens the distribution of potential outcomes, and in combination they create a risk profile that demands careful position sizing. The stability factor at the 53th percentile and quality factor at the 67th percentile provide a quantitative summary of the overall risk landscape.
Key risk mitigants include: healthy gross margins of 68% provide a buffer against cost pressures. These factors partially offset the identified risks and provide downside protection in adverse scenarios. On balance, the risk-reward profile is favorable for long-term investors.
We rate Caris Life Sciences, Inc.'s capital allocation as Standard. Management has shown adequate — though not exceptional — stewardship of shareholder capital. Returns on equity stand at 20.3%, and the balance sheet is managed within acceptable parameters (D/E: 79%). Exemplary allocators typically sustain ROE above 20% and D/E below 50%; Caris Life Sciences, Inc. falls short on at least one dimension.
There is room for improvement in optimizing the capital structure or enhancing shareholder returns. Absent a dividend, the overall capital allocation framework would benefit from either higher reinvestment returns, improved balance sheet efficiency, or increased shareholder distributions. We will monitor for signs of strategic improvement that could warrant an upgrade.
In summary, Caris Life Sciences, Inc. receives a Reduce rating with a composite score of 47.5/100 (rank #2413 of 7,333). Our quantitative framework assigns a Narrow Moat (53/100, trend: stable), Medium uncertainty, and Standard capital allocation. The average factor score across quality, value, momentum, stability, and investment is 43/100.
Our analysis does not support a constructive view on Caris Life Sciences, Inc. at this time. The combination of the current quantitative profile, medium uncertainty, and standard capital allocation suggests unfavorable risk-reward at current levels. We recommend investors avoid new positions and existing holders consider reducing exposure.
Analysis derived from Blank Capital Research quantitative terminal. For informational purposes only. No trade solicitation. Past performance not indicative of future results. Consult a qualified advisor.
We assign Caris Life Sciences, Inc. a Narrow Moat rating with a composite moat score of 53/100. The company possesses identifiable competitive advantages, though they are less entrenched than those of wide-moat peers. Our analysis indicates that Caris Life Sciences, Inc. can sustain above-average returns on invested capital for at least 10 years, with the strongest contributor being margin superiority at 13.5/20.
The strongest moat sources are margin superiority (13.5/20) and growth durability (13/20). GM 68% vs sector 60%, OM 15% vs sector 4%. Rev growth 113%. These pillars form the core of Caris Life Sciences, Inc.'s competitive identity and are the primary drivers of excess returns in our framework.
Areas of relative weakness include reinvestment efficiency (4.1/20) and financial resilience (10.8/20). Capital turnover N/A, R&D intensity 11.7%. Improvement in these areas could meaningfully widen the moat over time, while deterioration would be an early warning of competitive erosion.
Our moat trend assessment is Stable. Multi-year ROIC and operating margin trajectories show neither meaningful improvement nor deterioration, suggesting the competitive position is steady. We expect Caris Life Sciences, Inc.'s moat profile to remain largely unchanged absent a material shift in return on capital or industry dynamics.
Key profit drivers include gross margins of 68% providing a solid profitability foundation, operating margins of 15% reflecting effective cost management, robust top-line growth of 113% expanding the revenue base. The margin cascade from 68% gross to 15% operating to 11.2% net reveals the company's cost structure and reinvestment intensity. Our analysis indicates that the profit engine is high-quality and likely sustainable, with the quality factor at the 67th percentile.
The margin profile shows gross margins of 68%, operating margins of 15%, net margins of 11.2%. Return metrics include ROE of 20.3% and ROA of 9.9%. Relative to the Services sector, gross margins are 8.4 percentage points above the sector median of 60%, and ROE of 20.3% compares to a sector median of 5.3%.
The balance sheet reflects moderate leverage with D/E of 79%, revenue growth of 113%. The sector median D/E is 0%, putting Caris Life Sciences, Inc. at higher leverage than the typical peer. Overall balance sheet health is adequate for the current business environment.
A P/E of 196.0x leaves little room for execution misses — any earnings disappointment could trigger a sharp multiple compression.
Weak momentum (27th percentile) suggests institutional selling pressure and unfavorable technical dynamics that may persist.
Elevated short interest (74th percentile) indicates that sophisticated market participants are betting against the stock.
Insiders at Caris Life Sciences, Inc. (NASDAQ: CAI) have significantly increased their stock holdings over the past year, indicating growing optimism about the company's future. The Executive Vice Chairman made a notable purchase of US$630k worth of shares at a price close to the current market value. This bullish trend, coupled with substantial insider ownership of 48% (US$3.0 billion), suggests that insiders are incentivized to enhance the company's long-term value for all shareholders.

Caris Life Sciences announced preliminary, unaudited financial results for Q4 and full year 2025, showing significant revenue growth. Total revenue increased by approximately 116% in Q4 to $281 million and by 94% for the full year to $800 million, primarily driven by molecular profiling services. The company also reported strong growth in clinical therapy selection cases and an increase in cash and marketable securities, with these results being presented at the 44th Annual J.P. Morgan Healthcare Conference.

Caris Life Sciences (NASDAQ: CAI), a TechBio company and precision medicine pioneer, announced its plan to present at the 44th Annual J.P. Morgan Healthcare Conference. The presentation and Q&A session will occur on Monday, January 12 at 1:30 PM PT, and webcasts will be available on their investor relations website. The conference is scheduled for January 12-15, 2026, in San Francisco, California.

Caris Life Sciences (NASDAQ: CAI) has selected 15 physician-scientists for its 2025/2026 Caris Precision Oncology Alliance (POA) Fellows Forum, a two-year program focusing on precision medicine. The fellows will receive mentorship, hands-on training, and access to Caris' extensive CODEai database, which contains molecular data for over 484,000 cancer patients. This initiative aims to advance oncology research and accelerate discoveries in cancer diagnosis and treatment.
Caris Life Sciences, a cancer diagnostics company, plans to go public with a $400 million Nasdaq IPO, aiming for a valuation over $5.2 billion. The company has seen significant revenue growth, driven by its genomic profiling and liquid biopsy tests, and utilizes AI and machine learning to identify novel pathogenic mutations. Founder and CEO David Halbert is expected to own a significant stake after the offering.
Above 50MA
37.18%
Net New Highs
+51081