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Verdict
Quantitative factor alignment verified for current market regime.
Quant Score
Rank
#1871
Positioning
Market Dominance
Manufacturing
Pharmaceutical Products
$2.5B
Bobak Azamian
Tarsus Pharmaceuticals, Inc. focuses on the development and commercialization of novel therapeutic candidates for ophthalmic conditions. Its lead product candidate is TP-03, a novel therapeutic that is in Phase III for the treatment of blepharitis caused by the infestation of Demodex mites, as well as to treat meibomian gland disease. The company is also developing TP-04 for the. treatment of rosacea; and TP-05 for Lyme prophylaxis and community malaria reduction.
Headcount
50
HQ Base
Pending Verification
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| Stock | Rating | Score▼ | Quality | Value | Momentum | P/E | EV/EBITDA | ROE | ROA | Gross Mgn | Op Mgn | Net Mgn | Rev Growth | Div Yield | D/E | Mkt Cap | AUDIT |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
$UL UNILEVER PLC | 78 | 96 | 98 | 59 | - | - | 28.5% | 8.0% | 100.0% | 100.0% | 10.4% | -4.6% | 3.3% | 0.0x | $141.8B | VS | |
$ASML ASML HOLDING NV | 77 | 89 | 86 | 83 | - | - | 46.1% | 16.6% | 51.3% | 31.9% | 26.8% | -4.0% | 1.0% | 25.0x | $272.1B | VS | |
$ESLT ELBIT SYSTEMS LTD | 76 | 81 | 87 | 85 | - | - | 10.3% | 3.1% | 24.1% | 7.2% | 4.7% | 14.3% | 0.8% | 25.0x | $11.4B | VS | |
$MT ArcelorMittal | 75 | 71 | 98 | 85 | - | - | 2.2% | 1.5% | 9.3% | 5.3% | 2.2% | -8.5% | 2.2% | 16.0x | $18.9B | VS | |
$AMAT APPLIED MATERIALS INC /DE | 75 | 85 | 87 | 84 | 20.9x | 13.6x | 35.5% | 19.8% | 48.7% | 29.2% | 24.7% | 4.4% | 0.8% | 32.0x | $181.9B | VS | |
$SIMO Silicon Motion Technology CORP | 75 | 84 | 86 | 85 | - | - | 11.8% | 8.8% | 45.9% | 11.3% | 11.1% | 25.7% | 3.7% | 0.0x | $1.8B | VS | |
$CODA Coda Octopus Group, Inc. | 74 | 83 | 90 | 79 | 16.3x | 11.9x | 7.6% | 7.0% | 66.5% | 17.1% | 15.6% | 39.0% | 0.0% | 0.0x | $115M | VS | |
$GSK GSK plc | 74 | 84 | 90 | 70 | - | - | 22.6% | 4.9% | 71.2% | 12.8% | 9.4% | 1.7% | 5.9% | 124.0x | $72.1B | VS | |
$EFXT Enerflex Ltd. | 74 | 80 | 91 | 83 | - | - | 3.0% | 1.1% | 20.9% | 7.3% | 1.3% | 3.0% | 0.9% | 67.0x | $1.2B | VS | |
$BUD Anheuser-Busch InBev SA/NV | 74 | 84 | 97 | 63 | - | - | 8.2% | 3.5% | 55.3% | 25.9% | 12.4% | 0.7% | 1.7% | 0.0x | $87.0B | VS | |
$TARS Tarsus Pharmaceuticals, Inc. | 51 | 57 | 50 | 56 | - | - | -24.3% | -15.2% | 93.0% | -29.9% | -27.8% | 190.8% | 0.0% | 22.0x | $2.5B | ||
| SECTOR BENCH | - | - | - | - | - | 22.3x | 11.5x | -2.5% | -0.1% | 42.5% | 1.3% | -0.2% | 5.9% | 0.0% | 0.2x | - | REF |
Tarsus Pharmaceuticals, Inc. (TARS) receives a "Hold" rating with a composite score of 50.9/100. It ranks #1871 out of 7,333 stocks in our coverage universe and carries a 3-star rating. Ratings are driven by a 6-factor quantitative model measuring quality, value, momentum, investment, stability, and short interest.
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YOY expansion rate
Core pricing power
Operating efficiency
Bottom-line conversion
Equity capital efficiency
Asset base utilization
Financial leverage load
Direct cash return
Bobak Azamian
Chief Executive Officer
Labor Force
50
57
38
77
Audit Verdict: Average governance indicators based on financial metrics.
No recent insider transactions available for TARS
In-line with peers — no strong momentum signal
Fair valuation relative to peers
Average quality profile
Low volatility — smoother ride and historically better risk-adjusted returns
Moderate investment profile
Mid-range overall rating
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Relative valuation derived from Manufacturing sector benchmarks. Model weights: EV/EBITDA (40%), P/B (35%), P/S (25%). Re-calculated daily.
No analyst ratings for TARS.
View All RatingsHigh margin volatility — erratic forensic earnings quality
| Factor | Global | Sector | Tilt |
|---|---|---|---|
| PROFITABILITY | 57 | 48 | +9ALPHA |
| MOMENTUM | 56 | 47 | +9ALPHA |
| VALUATION | 50 | 29 | +21ALPHA |
| INVESTMENT | 38 | 68 | -30DRAG |
| STABILITY | 77 | 77 | 0NEUTRAL |
| SHORT INT | 16 | 1 | +15ALPHA |
Global = full universe. Sector = relative to industry peers. Positive tilt indicates idiosyncratic strength.
ROE proxy -24.3% (sector -2.5%)
GM 93% vs sector 43%, OM -30% vs sector 1%
Capital turnover N/A, R&D intensity 15.4%
Rev growth 191%, 6yr history
Interest coverage -6.4x
Composite assessment of profitability, capital efficiency, and financial strength. Top-tier entities demonstrate sustainable cash flow generation and elite competitive moats.
Profit generated per dollar of shareholder equity
Efficiency of asset utilization
Pricing power and cost efficiency
Core business profitability
Bottom-line profitability
The Quality factor evaluates the persistence and magnitude of realized cash flows. Companies with scores >70 exhibit superior pricing power and structural financial resilience through diverse economic regimes.
Our uncertainty rating tracks the predictability of future cash flows and potential for permanent capital loss. Moderate visibility with standard industry cyclicality.
Our model assigns Tarsus Pharmaceuticals, Inc. a Hold rating, with a composite score of 50.9/100 and 3 out of 5 stars. Ranked #1871 of 7,333 stocks, TARS presents a mixed quantitative picture — neither compelling enough to initiate new positions nor weak enough to warrant selling. Investors already holding may consider maintaining their position while monitoring for changes in the factor profile.
With a quality score of 57/100, TARS shows adequate but unremarkable business quality. The company reports a return on equity of -24.3% (sector avg: -2.5%), gross margins of 93.0% (sector avg: 42.5%), net margins of -27.8% (sector avg: -0.2%). This suggests the company generates acceptable returns but may lack the competitive positioning or operational efficiency to stand out from peers.
TARS's value score of 50/100 indicates the stock is fairly valued based on its current fundamentals. Key valuation metrics include a P/B ratio of 8.44x. At this level, neither a clear bargain nor overpriced, the stock's attractiveness depends more on forward growth expectations and qualitative factors.
Tarsus Pharmaceuticals, Inc.'s investment score of 38/100 suggests limited reinvestment activity. Key growth metrics include revenue growth of 190.8% vs. a sector average of 5.9% and a return on assets of -15.2% (sector: -0.1%). While this can be positive for mature, cash-generative businesses returning capital to shareholders, it may also signal a lack of growth opportunities or management conservatism.
TARS demonstrates moderate momentum with a score of 56/100, suggesting a neutral price trend without strong directional conviction. Revenue growth stands at 190.8% year-over-year, while a beta of 0.57 reflects its sensitivity to broader market moves. Moderate momentum may indicate the stock is consolidating or transitioning between trends, warranting close monitoring of upcoming catalysts.
TARS shows good financial stability with a score of 77/100. Key stability metrics include a beta of 0.57 and a debt-to-equity ratio of 22.00x (sector avg: 0.2x). This suggests manageable leverage and moderate price volatility, making it appropriate for investors seeking a balance between growth potential and capital preservation.
Tarsus Pharmaceuticals, Inc.'s short interest score of 16/100 reveals significant bearish positioning, suggesting institutional investors are actively betting against the stock. Specific risk factors include elevated leverage (D/E: 22.00x). At $2.5B (mid-cap), TARS carries meaningful risk and is best suited for investors with high risk tolerance who have thoroughly evaluated the bear thesis.
Tarsus Pharmaceuticals, Inc. is a mid-cap company in the Manufacturing sector, ranked #0 of 50 in its sector (100th percentile) and #1871 of 7,333 overall (74th percentile). Key comparisons include ROE of -24.3% trailing the -2.5% sector median and operating margins of -29.9% below the 1.3% sector average. This top-quartile standing reflects exceptional competitive strength relative to Manufacturing peers.
While TARS currently exhibits a HOLD profile, superior opportunities exist within the MANUFACTURING sector. Our model identifies several "Strong Buy" candidates with higher quality scores and more attractive valuations among direct industry competitors.
View Top Manufacturing Alpha →Quant Factor Profile
Key factor gap
Stability (77) vs Short Int. (16) — closing this gap could shift the rating.
ROE 880% ABOVE SECTOR MEDIAN (FAVORABLE)
Gross Margin 119% ABOVE SECTOR MEDIAN (FAVORABLE)
Op. Margin 2420% BELOW SECTOR MEDIAN
AUDIT DATA AS OF SEP 30, 2025 (Q2 FY2025)
We rate Tarsus Pharmaceuticals, Inc. (TARS) as a Hold with a composite score of 50.9/100 at a current price of $75.01. The stock presents a mixed quantitative picture — neither compelling enough to warrant new accumulation nor weak enough to justify selling for existing holders. Our factors are split, and the overall profile suggests patience is warranted.
The rating is primarily driven by strength in stability (77th percentile) and quality (57th percentile), which together account for the majority of the composite score. Offsetting weakness in investment (38th percentile) and value (50th percentile) tempers our overall conviction. We assign a No Moat rating (37/100), Medium uncertainty, and Poor capital allocation.
Key items to watch: sustainability of the current growth rate; the path to profitability. Any material change in these dynamics could warrant a reassessment of our rating. The moat trend is stable, which suggests the competitive landscape is stable for now.
Tarsus Pharmaceuticals, Inc. holds a top-quartile position (#0 of 50) within the Manufacturing sector, based on our composite quantitative scoring across quality, value, momentum, and stability factors. The composite score of 50.9/100 places it at rank #1871 in our full 7,333-stock universe. At $2.5B in market capitalization, Tarsus Pharmaceuticals, Inc. is a mid-cap player in the Manufacturing space, which limits certain scale advantages but may allow for more agile strategic execution.
Revenue is growing at 191%, though momentum at the 56th percentile suggests the market has not yet fully recognized this trajectory. This potential disconnect between fundamental improvement and market recognition could represent an opportunity for patient investors if the growth trend persists.
The margin cascade tells an important story: gross margins of 93% (+50.5pp vs sector) narrow to operating margins of -30% (-31.2pp vs sector) and net margins of -27.8%, yielding a gross-to-net conversion rate of -30%. The significant margin erosion from gross to net suggests elevated operating expenses, high interest costs, or other structural drags that warrant monitoring.
At a current price of $75.01, Tarsus Pharmaceuticals, Inc. is trading near fair value based on current fundamentals. Our value factor score of 50/100 reflects a composite assessment across multiple valuation metrics including price-to-earnings, price-to-book, EV/EBITDA, and price-to-sales ratios relative to both sector peers and the broader market. Valuation metrics are mixed, with no strong signal of mispricing in either direction.
The stock currently trades at P/B of 8.4x, P/S of 8.1x. We evaluate these multiples in the context of both absolute levels and sector-relative positioning to form our valuation view.
Gross margins of 93% signal strong pricing power and brand/IP advantages — businesses with margins above 40% have historically demonstrated more resilient earnings through economic cycles.
Revenue growth of 191% confirms the business is expanding its addressable market — growth at this level typically supports multiple expansion and attracts institutional capital.
A conservative balance sheet (22% D/E) provides financial flexibility for acquisitions, buybacks, or weathering economic downturns without dilution.
Thin net margins of -27.8% provide limited cushion against cost pressures, competitive pricing, or macroeconomic headwinds — even small changes in costs could swing the company to a loss.
We assign a Medium uncertainty rating to Tarsus Pharmaceuticals, Inc.. The stock presents a balanced risk profile: current negative profitability (net margin -27.8%) and low beta of 0.57 — while defensive, this may indicate limited upside participation in bull markets. While not risk-free, the core business fundamentals are adequate to withstand moderate economic stress, and the range of potential outcomes around our fair value estimate is manageable.
Specific risk factors that inform our assessment include: current negative profitability (net margin -27.8%); low beta of 0.57 — while defensive, this may indicate limited upside participation in bull markets. Each of these factors independently widens the distribution of potential outcomes, and in combination they create a risk profile that demands careful position sizing. The stability factor at the 77th percentile and quality factor at the 57th percentile provide a quantitative summary of the overall risk landscape.
Key risk mitigants include: healthy gross margins of 93% provide a buffer against cost pressures; conservative leverage (22% D/E) limits balance sheet risk; above-average stability (77th percentile) suggests predictable business dynamics. These factors partially offset the identified risks and provide downside protection in adverse scenarios. On balance, the risk-reward profile is favorable for long-term investors.
We rate Tarsus Pharmaceuticals, Inc.'s capital allocation as Poor. Key concerns include low returns on equity (-24.3%), negative profitability, weak asset returns (ROA -15.2%). Exemplary capital allocators generate ROE above 20% and maintain conservative leverage — Tarsus Pharmaceuticals, Inc. significantly underperforms these benchmarks, raising questions about management's ability to create shareholder value.
Investors should scrutinize management's reinvestment decisions and balance sheet trajectory before committing capital. Poor capital allocation often compounds over time: overlevered balance sheets limit strategic flexibility, while low returns on capital destroy shareholder value. We would need to see sustained improvement in profitability metrics and balance sheet discipline before considering an upgrade.
In summary, Tarsus Pharmaceuticals, Inc. receives a Hold rating with a composite score of 50.9/100 (rank #1871 of 7,333). Our quantitative framework assigns a No Moat (37/100, trend: stable), Medium uncertainty, and Poor capital allocation. The average factor score across quality, value, momentum, stability, and investment is 55/100.
Our analysis supports a neutral stance on Tarsus Pharmaceuticals, Inc.. While the quantitative profile is not weak enough to warrant selling, it lacks the multi-factor strength required for a buy recommendation. Existing holders should maintain positions and monitor for catalysts — either fundamental improvement or valuation compression — that would shift the risk-reward balance.
Analysis derived from Blank Capital Research quantitative terminal. For informational purposes only. No trade solicitation. Past performance not indicative of future results. Consult a qualified advisor.
We do not assign Tarsus Pharmaceuticals, Inc. a meaningful economic moat, scoring 37/100 on our composite assessment. Current fundamentals do not demonstrate the kind of durable competitive advantages — such as superior returns on invested capital, margin superiority, or reinvestment efficiency — that would protect the company from competitive erosion over the long term. The highest-scoring pillar, margin superiority, reached only 10.5/20.
The strongest moat sources are margin superiority (10.5/20) and growth durability (9.5/20). GM 93% vs sector 43%, OM -30% vs sector 1%. Rev growth 191%, 6yr history. These pillars form the core of Tarsus Pharmaceuticals, Inc.'s competitive identity and are the primary drivers of excess returns in our framework.
Areas of relative weakness include economic value creation (2.8/20) and reinvestment efficiency (5.4/20). ROE proxy -24.3% (sector -2.5%). Improvement in these areas could meaningfully widen the moat over time, while deterioration would be an early warning of competitive erosion.
Our moat trend assessment is Stable. Multi-year ROIC and operating margin trajectories show neither meaningful improvement nor deterioration, suggesting the competitive position is steady. We expect Tarsus Pharmaceuticals, Inc.'s moat profile to remain largely unchanged absent a material shift in return on capital or industry dynamics.
Key profit drivers include gross margins of 93% providing a solid profitability foundation, robust top-line growth of 191% expanding the revenue base. The margin cascade from 93% gross to -30% operating to -27.8% net reveals the company's cost structure and reinvestment intensity. Our analysis indicates that profit quality is adequate though not exceptional, with the quality factor at the 57th percentile.
The margin profile shows gross margins of 93%, operating margins of -30%, net margins of -27.8%. Return metrics include ROE of -24.3% and ROA of -15.2%. Relative to the Manufacturing sector, gross margins are 50.5 percentage points above the sector median of 43%, and ROE of -24.3% compares to a sector median of -2.5%.
The balance sheet reflects a conservatively managed balance sheet with D/E of 22%, revenue growth of 191%. The sector median D/E is 0%, putting Tarsus Pharmaceuticals, Inc. at higher leverage than the typical peer. Overall balance sheet health is adequate for the current business environment.
Above 50MA
37.18%
Net New Highs
+51081
Tarsus (TARS) Q4 2025 earnings call: XDEMVY sales surge, 2026 guidance $670–$700M, pipeline updates & risks.

Elanco Animal Health has sold certain future royalties and commercial milestones associated with its Xdemvy product to Blackstone for $295 million. The company will use the proceeds to reduce its debt and expects to achieve a net leverage ratio of 3.9x-4.3x EBITDA by the end of 2025.
Tarsus Pharmaceuticals (NASDAQ:TARS) reported fourth-quarter and full-year 2025 results highlighting rapid growth for XDEMVY, the company’s FDA-approved treatment for Demodex blepharitis (DB), and outlined a 2026 plan that includes first-time annual revenue guidance, a modest sales force expansion,

Capricorn Fund Managers Ltd acquired 484,500 shares of Phreesia, valued at $11.4 million, representing 3.8% of their reportable assets under management. The investment comes as Phreesia reaches a milestone of first quarterly net income and plans to expand payment solutions.