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Verdict
Quantitative factor alignment verified for current market regime.
Quant Score
Rank
#3890
Positioning
Market Dominance
Manufacturing
Pharmaceutical Products
$68M
Matthew C. Coffey
Oncolytics Biotech Inc. focuses on the discovery and development of pharmaceutical products for the treatment of cancer. Its lead product is pelareorep, an intravenously delivered immunotherapeutic agent. The company was incorporated in 1998 and is headquartered in Calgary, Canada.
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| Stock | Rating | Score▼ | Quality | Value | Momentum | P/E | EV/EBITDA | ROE | ROA | Gross Mgn | Op Mgn | Net Mgn | Rev Growth | Div Yield | D/E | Mkt Cap | AUDIT |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
$UL UNILEVER PLC | 78 | 96 | 98 | 59 | - | - | 28.5% | 8.0% | 100.0% | 100.0% | 10.4% | -4.6% | 3.3% | 0.0x | $141.8B | VS | |
$ASML ASML HOLDING NV | 77 | 89 | 86 | 83 | - | - | 46.1% | 16.6% | 51.3% | 31.9% | 26.8% | -4.0% | 1.0% | 25.0x | $272.1B | VS | |
$ESLT ELBIT SYSTEMS LTD | 76 | 81 | 87 | 85 | - | - | 10.3% | 3.1% | 24.1% | 7.2% | 4.7% | 14.3% | 0.8% | 25.0x | $11.4B | VS | |
$MT ArcelorMittal | 75 | 71 | 98 | 85 | - | - | 2.2% | 1.5% | 9.3% | 5.3% | 2.2% | -8.5% | 2.2% | 16.0x | $18.9B | VS | |
$AMAT APPLIED MATERIALS INC /DE | 75 | 85 | 87 | 84 | 20.9x | 13.6x | 35.5% | 19.8% | 48.7% | 29.2% | 24.7% | 4.4% | 0.8% | 32.0x | $181.9B | VS | |
$SIMO Silicon Motion Technology CORP | 75 | 84 | 86 | 85 | - | - | 11.8% | 8.8% | 45.9% | 11.3% | 11.1% | 25.7% | 3.7% | 0.0x | $1.8B | VS | |
$CODA Coda Octopus Group, Inc. | 74 | 83 | 90 | 79 | 16.3x | 11.9x | 7.6% | 7.0% | 66.5% | 17.1% | 15.6% | 39.0% | 0.0% | 0.0x | $115M | VS | |
$GSK GSK plc | 74 | 84 | 90 | 70 | - | - | 22.6% | 4.9% | 71.2% | 12.8% | 9.4% | 1.7% | 5.9% | 124.0x | $72.1B | VS | |
$EFXT Enerflex Ltd. | 74 | 80 | 91 | 83 | - | - | 3.0% | 1.1% | 20.9% | 7.3% | 1.3% | 3.0% | 0.9% | 67.0x | $1.2B | VS | |
$BUD Anheuser-Busch InBev SA/NV | 74 | 84 | 97 | 63 | - | - | 8.2% | 3.5% | 55.3% | 25.9% | 12.4% | 0.7% | 1.7% | 0.0x | $87.0B | VS | |
$ONCY ONCOLYTICS BIOTECH INC | 37 | 24 | 10 | 55 | - | - | -2120.0% | -628.3% | - | - | - | - | 0.0% | 0.0x | $68M | ||
| SECTOR BENCH | - | - | - | - | - | 22.3x | 11.5x | -2.5% | -0.1% | 42.5% | 1.3% | -0.2% | 5.9% | 0.0% | 0.2x | - | REF |
ONCOLYTICS BIOTECH INC (ONCY) receives a "Avoid" rating with a composite score of 37.1/100. It ranks #3890 out of 7,333 stocks in our coverage universe and carries a 1-star rating. Ratings are driven by a 6-factor quantitative model measuring quality, value, momentum, investment, stability, and short interest.
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Equity capital efficiency
Asset base utilization
Financial leverage load
Direct cash return
Matthew C. Coffey
Chief Executive Officer
Labor Force
30
24
54
37
Audit Verdict: Lower quality and stability scores may indicate governance concerns.
No recent insider transactions available for ONCY
In-line with peers — no strong momentum signal
Expensive relative to fundamentals — limited margin of safety
Weak fundamentals — higher risk of value trap
Average volatility — neutral timing signal
Moderate investment profile
Below-average composite — caution warranted
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Relative valuation derived from Manufacturing sector benchmarks. Model weights: EV/EBITDA (40%), P/B (35%), P/S (25%). Re-calculated daily.
No analyst ratings for ONCY.
View All RatingsInsufficient data for Financial Analysis
ROE proxy -2120.0% (sector -2.5%)
GM N/A vs sector 43%, OM N/A vs sector 1%
Capital turnover N/A
Rev growth N/A, 8yr history
Interest coverage N/A
Composite assessment of profitability, capital efficiency, and financial strength. Top-tier entities demonstrate sustainable cash flow generation and elite competitive moats.
Profit generated per dollar of shareholder equity
Efficiency of asset utilization
Pricing power and cost efficiency
Core business profitability
Bottom-line profitability
The Quality factor evaluates the persistence and magnitude of realized cash flows. Companies with scores >70 exhibit superior pricing power and structural financial resilience through diverse economic regimes.
Our uncertainty rating tracks the predictability of future cash flows and potential for permanent capital loss. Moderate visibility with standard industry cyclicality.
Our quantitative model flags ONCOLYTICS BIOTECH INC with an Avoid rating, assigning a composite score of 37.1/100 and 1 out of 5 stars. Ranked #3890 of 7,333 stocks, ONCY falls in the bottom tier across key factors. Historically, stocks with this profile have faced elevated risk of underperformance and capital loss.
ONCOLYTICS BIOTECH INC registers a weak quality score of just 24/100, indicating significant profitability challenges. The company reports a return on equity of -2120.0% (sector avg: -2.5%). Low quality scores are often associated with businesses in turnaround mode, early-stage growth, or structurally challenged industries.
ONCY registers a value score of just 10/100, suggesting the stock trades at a significant premium to its fundamental metrics. Key valuation metrics include a P/B ratio of 24.86x. High-premium valuations like this require strong future execution to avoid multiple compression, and downside risk is elevated if growth disappoints.
With an investment score of 54/100, ONCY exhibits moderate growth-oriented spending. Key growth metrics include a return on assets of -628.3% (sector: -0.1%). The company appears to be balancing growth investments with capital returns, though the pace of investment may not be enough to accelerate top-line growth meaningfully.
ONCY demonstrates moderate momentum with a score of 55/100, suggesting a neutral price trend without strong directional conviction. Revenue growth data is not currently available, while a beta of 0.80 reflects its sensitivity to broader market moves. Moderate momentum may indicate the stock is consolidating or transitioning between trends, warranting close monitoring of upcoming catalysts.
ONCY's stability score of 37/100 signals elevated volatility and/or leverage concerns. Key stability metrics include a beta of 0.80 and a debt-to-equity ratio of 0.00x (sector avg: 0.2x). Investors should be prepared for wider-than-average price swings and consider position sizing accordingly to manage portfolio risk.
The short interest score of 59/100 for ONCY suggests somewhat elevated bearish positioning by institutional traders. Specific risk factors include micro-cap liquidity risk. With a $68M market cap (micro-cap), ONCOLYTICS BIOTECH INC may experience above-average volatility. Investors should consider whether the short thesis has merit or if it creates a potential short-squeeze opportunity.
ONCOLYTICS BIOTECH INC is a micro-cap company in the Manufacturing sector, ranked #0 of 50 in its sector (100th percentile) and #3890 of 7,333 overall (47th percentile). Key comparisons include ROE of -2120.0% trailing the -2.5% sector median. This top-quartile standing reflects exceptional competitive strength relative to Manufacturing peers.
While ONCY currently exhibits a AVOID profile, superior opportunities exist within the MANUFACTURING sector. Our model identifies several "Strong Buy" candidates with higher quality scores and more attractive valuations among direct industry competitors.
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Improvement in Value (10) would have the largest impact on the composite score.
ROE 85384% ABOVE SECTOR MEDIAN (FAVORABLE)
Debt/Equity 100% BELOW SECTOR MEDIAN (FAVORABLE)
Div. Yield NaN% BELOW SECTOR MEDIAN
AUDIT DATA AS OF DEC 31, 2024 (Q3 FY2024)
We rate ONCOLYTICS BIOTECH INC (ONCY) as Avoid with a composite score of 37.1/100 at a current price of $1.16. The stock falls in the bottom quintile of our universe across key quantitative factors, and the multi-factor weakness suggests a high probability of continued underperformance.
The rating is primarily driven by strength in momentum (55th percentile) and investment (54th percentile), which together account for the majority of the composite score. Offsetting weakness in value (10th percentile) and quality (24th percentile) tempers our overall conviction. We assign a No Moat rating (20/100), Medium uncertainty, and Poor capital allocation.
Key items to watch: valuation compression risk if growth disappoints. Any material change in these dynamics could warrant a reassessment of our rating. The moat trend is stable, which suggests the competitive landscape is stable for now.
ONCOLYTICS BIOTECH INC holds a top-quartile position (#0 of 50) within the Manufacturing sector, based on our composite quantitative scoring across quality, value, momentum, and stability factors. The composite score of 37.1/100 places it at rank #3890 in our full 7,333-stock universe. At $68M in market capitalization, ONCOLYTICS BIOTECH INC is a small-cap player in the Manufacturing space, which limits certain scale advantages but may allow for more agile strategic execution.
Momentum indicators (55th percentile) are neutral regarding the near-term price trend. Revenue growth data is unavailable, limiting our ability to confirm whether momentum is fundamentally supported.
Margin data is not available for ONCOLYTICS BIOTECH INC, which limits our assessment of the company's cost structure and operating efficiency. We rely on factor-based signals to infer business quality in the absence of detailed margin data.
At a current price of $1.16, ONCOLYTICS BIOTECH INC is trading at a premium to fundamental value. Our value factor score of 10/100 reflects a composite assessment across multiple valuation metrics including price-to-earnings, price-to-book, EV/EBITDA, and price-to-sales ratios relative to both sector peers and the broader market. The premium valuation implies the market is pricing in significant future growth or quality improvements that are not yet fully reflected in current fundamentals.
The stock currently trades at P/B of 24.9x. We evaluate these multiples in the context of both absolute levels and sector-relative positioning to form our valuation view.
A conservative balance sheet (0% D/E) provides financial flexibility for acquisitions, buybacks, or weathering economic downturns without dilution.
The Avoid rating (composite 37.1/100) reflects multi-factor weakness, and historically, stocks in this scoring range have underperformed the market by a meaningful margin.
Below-average quality (24th percentile) raises durability concerns about the fundamental profile and increases the risk of negative earnings surprises.
We assign a Medium uncertainty rating to ONCOLYTICS BIOTECH INC. The stock presents a balanced risk profile: below-average price stability (37th percentile) and weak quality scores (24th percentile). While not risk-free, the core business fundamentals are adequate to withstand moderate economic stress, and the range of potential outcomes around our fair value estimate is manageable.
Specific risk factors that inform our assessment include: below-average price stability (37th percentile); weak quality scores (24th percentile). Each of these factors independently widens the distribution of potential outcomes, and in combination they create a risk profile that demands careful position sizing. The stability factor at the 37th percentile and quality factor at the 24th percentile provide a quantitative summary of the overall risk landscape.
Key risk mitigants include: conservative leverage (0% D/E) limits balance sheet risk. These factors partially offset the identified risks and provide downside protection in adverse scenarios. On balance, the risk-reward profile is favorable for long-term investors.
We rate ONCOLYTICS BIOTECH INC's capital allocation as Poor. Key concerns include low returns on equity (-2120.0%), weak asset returns (ROA -628.3%). Exemplary capital allocators generate ROE above 20% and maintain conservative leverage — ONCOLYTICS BIOTECH INC significantly underperforms these benchmarks, raising questions about management's ability to create shareholder value.
Investors should scrutinize management's reinvestment decisions and balance sheet trajectory before committing capital. Poor capital allocation often compounds over time: overlevered balance sheets limit strategic flexibility, while low returns on capital destroy shareholder value. We would need to see sustained improvement in profitability metrics and balance sheet discipline before considering an upgrade.
In summary, ONCOLYTICS BIOTECH INC receives a Avoid rating with a composite score of 37.1/100 (rank #3890 of 7,333). Our quantitative framework assigns a No Moat (20/100, trend: stable), Medium uncertainty, and Poor capital allocation. The average factor score across quality, value, momentum, stability, and investment is 36/100.
Our analysis does not support a constructive view on ONCOLYTICS BIOTECH INC at this time. The combination of limited competitive advantages, medium uncertainty, and poor capital allocation suggests unfavorable risk-reward at current levels. We recommend investors avoid new positions and existing holders consider reducing exposure.
Analysis derived from Blank Capital Research quantitative terminal. For informational purposes only. No trade solicitation. Past performance not indicative of future results. Consult a qualified advisor.
We do not assign ONCOLYTICS BIOTECH INC a meaningful economic moat, scoring 20/100 on our composite assessment. Current fundamentals do not demonstrate the kind of durable competitive advantages — such as superior returns on invested capital, margin superiority, or reinvestment efficiency — that would protect the company from competitive erosion over the long term. The highest-scoring pillar, margin superiority, reached only 10/20.
The strongest moat sources are margin superiority (10/20) and financial resilience (7/20). GM N/A vs sector 43%, OM N/A vs sector 1%. Interest coverage N/A. These pillars form the core of ONCOLYTICS BIOTECH INC's competitive identity and are the primary drivers of excess returns in our framework.
Areas of relative weakness include reinvestment efficiency (0/20) and growth durability (0/20). Capital turnover N/A. Improvement in these areas could meaningfully widen the moat over time, while deterioration would be an early warning of competitive erosion.
Our moat trend assessment is Stable. Multi-year ROIC and operating margin trajectories show neither meaningful improvement nor deterioration, suggesting the competitive position is steady. We expect ONCOLYTICS BIOTECH INC's moat profile to remain largely unchanged absent a material shift in return on capital or industry dynamics.
Key profit drivers are not clearly identifiable from current fundamentals. This may reflect a company in transition, a cyclical downturn, or structural challenges in the business model. We assign a quality factor of 24/100 which further underscores our concern regarding earnings sustainability.
Return metrics include ROE of -2120.0% and ROA of -628.3%. Relative to the Manufacturing sector, sector comparison data is limited, and ROE of -2120.0% compares to a sector median of -2.5%.
The balance sheet reflects a conservatively managed balance sheet with D/E of 0%. The sector median D/E is 0%, putting ONCOLYTICS BIOTECH INC in a relatively stronger balance sheet position. Overall balance sheet health is adequate for the current business environment.
Above 50MA
37.18%
Net New Highs
+51081

Seven brokerages have issued a consensus "Moderate Buy" rating for Oncolytics Biotech Inc. (NASDAQ:ONCY), with an average 12-month price target of $6.25. The company recently reported better-than-expected quarterly earnings, and there has been significant insider buying totaling over $348,000 in the last 90 days. Despite a mixed analyst outlook, shares opened up 27% at $1.06.

Oncolytics Biotech (NASDAQ:ONCY) CEO Jared Kelly recently increased his direct stake in the company by 37.11%, purchasing 29,500 shares at $0.84 each on February 12th, following an earlier purchase of 5,600 shares on February 11th. These transactions bring his total direct ownership to 109,000 shares. The clinical-stage biotech company is developing pelareorep for cancer treatment and holds a "Moderate Buy" consensus rating from analysts with an average price target of $6.25.

Oncolytics Biotech Inc. (NASDAQ: ONCY) has seen its stock rise by 14.99% due to investor enthusiasm over recent immunotherapy breakthroughs. The company's strategic board expansions and leadership appointments, along with promising clinical trial results for its drug Pelareorep, position it as a potential leader in oncology therapeutics. Despite financial challenges common in biotech, Oncolytics is managing its cash flow and leveraging its innovations for long-term growth.

Oncolytics Biotech Inc. (NASDAQ:ONCY) stock surged 16.2% after the FDA granted Fast Track Designation for its pelareorep therapy aimed at treating KRAS-mutant, microsatellite-stable metastatic colorectal cancer. This designation is based on clinical data showing significantly improved objective response rates and survival metrics compared to standard care, positioning pelareorep as a potential platform immunotherapy for gastrointestinal cancers. The company plans to initiate a controlled clinical study in March, with interim data expected by year-end 2026.

This article highlights how the oncology clinical trials market is shifting towards `registration-ready` platforms, with investors focusing on late-stage and newly commercial companies. It specifically examines Oncolytics Biotech Inc. (NASDAQ: ONCY), BioNTech (NASDAQ: BNTX), MAIA Biotechnology (NYSE-A: MAIA), Acrivon Therapeutics (NASDAQ: ACRV), and ImmunityBio (NASDAQ: IBRX) as key players making significant advancements in cancer treatment. The article details their recent clinical breakthroughs, strategic appointments, and regulatory achievements, positioning them for potential rapid maturation and M&A activity in 2026.