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Verdict
Quantitative factor alignment verified for current market regime.
Quant Score
Rank
#3595
Positioning
Market Dominance
Manufacturing
Pharmaceutical Products
$2.0B
Antony Mattessich
Ocular Therapeutix, Inc. focuses on the formulation, development, and commercialization of therapies for diseases and conditions of the eye. The company markets ReSure Sealant, an ophthalmic device to prevent wound leaks in corneal incisions following cataract surgery. It is also developing OTX-TKI, an axitinib intravitreal implant that is in phase 1 clinical trials for the treatment of wet age-related macular degeneration and other retinal diseases.
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| Stock | Rating | Score▼ | Quality | Value | Momentum | P/E | EV/EBITDA | ROE | ROA | Gross Mgn | Op Mgn | Net Mgn | Rev Growth | Div Yield | D/E | Mkt Cap | AUDIT |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
$UL UNILEVER PLC | 78 | 96 | 98 | 59 | - | - | 28.5% | 8.0% | 100.0% | 100.0% | 10.4% | -4.6% | 3.3% | 0.0x | $141.8B | VS | |
$ASML ASML HOLDING NV | 77 | 89 | 86 | 83 | - | - | 46.1% | 16.6% | 51.3% | 31.9% | 26.8% | -4.0% | 1.0% | 25.0x | $272.1B | VS | |
$ESLT ELBIT SYSTEMS LTD | 76 | 81 | 87 | 85 | - | - | 10.3% | 3.1% | 24.1% | 7.2% | 4.7% | 14.3% | 0.8% | 25.0x | $11.4B | VS | |
$MT ArcelorMittal | 75 | 71 | 98 | 85 | - | - | 2.2% | 1.5% | 9.3% | 5.3% | 2.2% | -8.5% | 2.2% | 16.0x | $18.9B | VS | |
$AMAT APPLIED MATERIALS INC /DE | 75 | 85 | 87 | 84 | 20.9x | 13.6x | 35.5% | 19.8% | 48.7% | 29.2% | 24.7% | 4.4% | 0.8% | 32.0x | $181.9B | VS | |
$SIMO Silicon Motion Technology CORP | 75 | 84 | 86 | 85 | - | - | 11.8% | 8.8% | 45.9% | 11.3% | 11.1% | 25.7% | 3.7% | 0.0x | $1.8B | VS | |
$CODA Coda Octopus Group, Inc. | 74 | 83 | 90 | 79 | 16.3x | 11.9x | 7.6% | 7.0% | 66.5% | 17.1% | 15.6% | 39.0% | 0.0% | 0.0x | $115M | VS | |
$GSK GSK plc | 74 | 84 | 90 | 70 | - | - | 22.6% | 4.9% | 71.2% | 12.8% | 9.4% | 1.7% | 5.9% | 124.0x | $72.1B | VS | |
$EFXT Enerflex Ltd. | 74 | 80 | 91 | 83 | - | - | 3.0% | 1.1% | 20.9% | 7.3% | 1.3% | 3.0% | 0.9% | 67.0x | $1.2B | VS | |
$BUD Anheuser-Busch InBev SA/NV | 74 | 84 | 97 | 63 | - | - | 8.2% | 3.5% | 55.3% | 25.9% | 12.4% | 0.7% | 1.7% | 0.0x | $87.0B | VS | |
$OCUL OCULAR THERAPEUTIX, INC | 40 | 34 | 38 | 43 | - | - | -36.3% | -29.4% | 87.9% | -467.6% | -454.1% | -11.5% | 0.0% | 23.0x | $2.0B | ||
| SECTOR BENCH | - | - | - | - | - | 22.3x | 11.5x | -2.5% | -0.1% | 42.5% | 1.3% | -0.2% | 5.9% | 0.0% | 0.2x | - | REF |
OCULAR THERAPEUTIX, INC (OCUL) receives a "Avoid" rating with a composite score of 39.6/100. It ranks #3595 out of 7,333 stocks in our coverage universe and carries a 1-star rating. Ratings are driven by a 6-factor quantitative model measuring quality, value, momentum, investment, stability, and short interest.
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YOY expansion rate
Core pricing power
Operating efficiency
Bottom-line conversion
Equity capital efficiency
Asset base utilization
Financial leverage load
Direct cash return
Antony Mattessich
Chief Executive Officer
Labor Force
230
34
33
40
Audit Verdict: Lower quality and stability scores may indicate governance concerns.
No recent insider transactions available for OCUL
In-line with peers — no strong momentum signal
Fair valuation relative to peers
Weak fundamentals — higher risk of value trap
Average volatility — neutral timing signal
Aggressive spending — empire-building risk, dilutive growth
Below-average composite — caution warranted
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Relative valuation derived from Manufacturing sector benchmarks. Model weights: EV/EBITDA (40%), P/B (35%), P/S (25%). Re-calculated daily.
No analyst ratings for OCUL.
View All RatingsImproving capital utilization rates confirmed
High margin volatility — erratic forensic earnings quality
ROE proxy -36.3% (sector -2.5%)
GM 88% vs sector 43%, OM -468% vs sector 1%
Capital turnover N/A, R&D intensity 379.4%
Rev growth -12%, 10yr history
Interest coverage -89.9x
Composite assessment of profitability, capital efficiency, and financial strength. Top-tier entities demonstrate sustainable cash flow generation and elite competitive moats.
Profit generated per dollar of shareholder equity
Efficiency of asset utilization
Pricing power and cost efficiency
Core business profitability
Bottom-line profitability
The Quality factor evaluates the persistence and magnitude of realized cash flows. Companies with scores >70 exhibit superior pricing power and structural financial resilience through diverse economic regimes.
Our uncertainty rating tracks the predictability of future cash flows and potential for permanent capital loss. Moderate visibility with standard industry cyclicality.
Our quantitative model flags OCULAR THERAPEUTIX, INC with an Avoid rating, assigning a composite score of 39.6/100 and 1 out of 5 stars. Ranked #3595 of 7,333 stocks, OCUL falls in the bottom tier across key factors. Historically, stocks with this profile have faced elevated risk of underperformance and capital loss.
OCUL's quality score of 34/100 is below average, suggesting challenges with profitability or capital efficiency. The company reports a return on equity of -36.3% (sector avg: -2.5%), gross margins of 87.9% (sector avg: 42.5%), net margins of -454.1% (sector avg: -0.2%). Investors should examine whether management is actively addressing these weaknesses or if they reflect structural industry headwinds.
With a value score of 38/100, OCUL appears somewhat expensive relative to its fundamentals. Key valuation metrics include a P/B ratio of 2.59x. Investors paying a premium here are likely betting on above-average growth or margin expansion to justify current prices.
OCULAR THERAPEUTIX, INC's investment score of 33/100 suggests limited reinvestment activity. Key growth metrics include revenue growth of -11.5% vs. a sector average of 5.9% and a return on assets of -29.4% (sector: -0.1%). While this can be positive for mature, cash-generative businesses returning capital to shareholders, it may also signal a lack of growth opportunities or management conservatism.
OCUL is currently showing below-average momentum at 43/100, which may indicate weakening institutional interest or negative sentiment shifts. Revenue growth stands at -11.5% year-over-year, while a beta of 1.13 reflects its sensitivity to broader market moves. Investors should note that declining momentum can precede further price weakness, though contrarian opportunities sometimes emerge at these levels.
OCUL's stability score of 40/100 signals elevated volatility and/or leverage concerns. Key stability metrics include a beta of 1.13 and a debt-to-equity ratio of 23.00x (sector avg: 0.2x). Investors should be prepared for wider-than-average price swings and consider position sizing accordingly to manage portfolio risk.
OCUL carries a short interest score of 68/100, indicating moderate short selling activity. This is a neutral reading — not enough to signal systemic bearishness, but worth monitoring. Specific risk factors include elevated leverage (D/E: 23.00x). At $2.0B market cap (mid-cap), OCULAR THERAPEUTIX, INC offers reasonable institutional liquidity.
OCULAR THERAPEUTIX, INC is a mid-cap company in the Manufacturing sector, ranked #0 of 50 in its sector (100th percentile) and #3595 of 7,333 overall (51st percentile). Key comparisons include ROE of -36.3% trailing the -2.5% sector median and operating margins of -467.6% below the 1.3% sector average. This top-quartile standing reflects exceptional competitive strength relative to Manufacturing peers.
While OCUL currently exhibits a AVOID profile, superior opportunities exist within the MANUFACTURING sector. Our model identifies several "Strong Buy" candidates with higher quality scores and more attractive valuations among direct industry competitors.
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Improvement in Investment (33) would have the largest impact on the composite score.
ROE 1365% ABOVE SECTOR MEDIAN (FAVORABLE)
Gross Margin 107% ABOVE SECTOR MEDIAN (FAVORABLE)
Op. Margin 36352% BELOW SECTOR MEDIAN
AUDIT DATA AS OF SEP 30, 2025 (Q2 FY2025)
We rate OCULAR THERAPEUTIX, INC (OCUL) as Avoid with a composite score of 39.6/100 at a current price of $8.97. The stock falls in the bottom quintile of our universe across key quantitative factors, and the multi-factor weakness suggests a high probability of continued underperformance.
The rating is primarily driven by strength in momentum (43th percentile) and stability (40th percentile), which together account for the majority of the composite score. Offsetting weakness in investment (33th percentile) and quality (34th percentile) tempers our overall conviction. We assign a No Moat rating (33/100), High uncertainty, and Poor capital allocation.
Key items to watch: the path to profitability. Any material change in these dynamics could warrant a reassessment of our rating. The moat trend is stable, which suggests the competitive landscape is stable for now.
OCULAR THERAPEUTIX, INC holds a top-quartile position (#0 of 50) within the Manufacturing sector, based on our composite quantitative scoring across quality, value, momentum, and stability factors. The composite score of 39.6/100 places it at rank #3595 in our full 7,333-stock universe. At $2.0B in market capitalization, OCULAR THERAPEUTIX, INC is a mid-cap player in the Manufacturing space, which limits certain scale advantages but may allow for more agile strategic execution.
Revenue contraction of -12% combined with momentum at the 43th percentile paints a cautious picture of the near-term business outlook. The market appears to be pricing in continued challenges, and a catalyst for reversal is not clearly visible from current data.
The margin cascade tells an important story: gross margins of 88% (+45.4pp vs sector) narrow to operating margins of -468% (-468.9pp vs sector) and net margins of -454.1%, yielding a gross-to-net conversion rate of -517%. The significant margin erosion from gross to net suggests elevated operating expenses, high interest costs, or other structural drags that warrant monitoring.
At a current price of $8.97, OCULAR THERAPEUTIX, INC is trading at a premium to fundamental value. Our value factor score of 38/100 reflects a composite assessment across multiple valuation metrics including price-to-earnings, price-to-book, EV/EBITDA, and price-to-sales ratios relative to both sector peers and the broader market. The premium valuation implies the market is pricing in significant future growth or quality improvements that are not yet fully reflected in current fundamentals.
The stock currently trades at P/B of 2.6x, P/S of 31.3x. We evaluate these multiples in the context of both absolute levels and sector-relative positioning to form our valuation view.
Gross margins of 88% signal strong pricing power and brand/IP advantages — businesses with margins above 40% have historically demonstrated more resilient earnings through economic cycles.
A conservative balance sheet (23% D/E) provides financial flexibility for acquisitions, buybacks, or weathering economic downturns without dilution.
The Avoid rating (composite 39.6/100) reflects multi-factor weakness, and historically, stocks in this scoring range have underperformed the market by a meaningful margin.
Revenue decline of -12% signals business deterioration — declining revenues make it difficult to grow into the current valuation and often precede further negative revisions.
Thin net margins of -454.1% provide limited cushion against cost pressures, competitive pricing, or macroeconomic headwinds — even small changes in costs could swing the company to a loss.
We assign a High uncertainty rating to OCULAR THERAPEUTIX, INC. Key risk factors include current negative profitability (net margin -454.1%), below-average price stability (40th percentile), weak quality scores (34th percentile). The wide range of potential outcomes widens our fair value estimate and increases the possibility of permanent capital impairment. Investors considering this name should size positions accordingly and demand a meaningful margin of safety before initiating.
Specific risk factors that inform our assessment include: current negative profitability (net margin -454.1%); below-average price stability (40th percentile); weak quality scores (34th percentile). Each of these factors independently widens the distribution of potential outcomes, and in combination they create a risk profile that demands careful position sizing. The stability factor at the 40th percentile and quality factor at the 34th percentile provide a quantitative summary of the overall risk landscape.
Key risk mitigants include: healthy gross margins of 88% provide a buffer against cost pressures; conservative leverage (23% D/E) limits balance sheet risk. These factors partially offset the identified risks and provide downside protection in adverse scenarios. On balance, the risk-reward profile warrants caution and disciplined position management.
We rate OCULAR THERAPEUTIX, INC's capital allocation as Poor. Key concerns include low returns on equity (-36.3%), negative profitability, weak asset returns (ROA -29.4%). Exemplary capital allocators generate ROE above 20% and maintain conservative leverage — OCULAR THERAPEUTIX, INC significantly underperforms these benchmarks, raising questions about management's ability to create shareholder value.
Investors should scrutinize management's reinvestment decisions and balance sheet trajectory before committing capital. Poor capital allocation often compounds over time: overlevered balance sheets limit strategic flexibility, while low returns on capital destroy shareholder value. We would need to see sustained improvement in profitability metrics and balance sheet discipline before considering an upgrade.
In summary, OCULAR THERAPEUTIX, INC receives a Avoid rating with a composite score of 39.6/100 (rank #3595 of 7,333). Our quantitative framework assigns a No Moat (33/100, trend: stable), High uncertainty, and Poor capital allocation. The average factor score across quality, value, momentum, stability, and investment is 38/100.
Our analysis does not support a constructive view on OCULAR THERAPEUTIX, INC at this time. The combination of limited competitive advantages, high uncertainty, and poor capital allocation suggests unfavorable risk-reward at current levels. We recommend investors avoid new positions and existing holders consider reducing exposure.
Analysis derived from Blank Capital Research quantitative terminal. For informational purposes only. No trade solicitation. Past performance not indicative of future results. Consult a qualified advisor.
We do not assign OCULAR THERAPEUTIX, INC a meaningful economic moat, scoring 33/100 on our composite assessment. Current fundamentals do not demonstrate the kind of durable competitive advantages — such as superior returns on invested capital, margin superiority, or reinvestment efficiency — that would protect the company from competitive erosion over the long term. The highest-scoring pillar, margin superiority, reached only 12.7/20.
The strongest moat sources are margin superiority (12.7/20) and reinvestment efficiency (7/20). GM 88% vs sector 43%, OM -468% vs sector 1%. Capital turnover N/A, R&D intensity 379.4%. These pillars form the core of OCULAR THERAPEUTIX, INC's competitive identity and are the primary drivers of excess returns in our framework.
Areas of relative weakness include economic value creation (0.1/20) and growth durability (6.3/20). ROE proxy -36.3% (sector -2.5%). Improvement in these areas could meaningfully widen the moat over time, while deterioration would be an early warning of competitive erosion.
Our moat trend assessment is Stable. Multi-year ROIC and operating margin trajectories show neither meaningful improvement nor deterioration, suggesting the competitive position is steady. We expect OCULAR THERAPEUTIX, INC's moat profile to remain largely unchanged absent a material shift in return on capital or industry dynamics.
Key profit drivers include gross margins of 88% providing a solid profitability foundation, declining revenues (-12%) that pressure the earnings outlook. The margin cascade from 88% gross to -468% operating to -454.1% net reveals the company's cost structure and reinvestment intensity. Our analysis indicates that profit quality raises some durability concerns, with the quality factor at the 34th percentile.
The margin profile shows gross margins of 88%, operating margins of -468%, net margins of -454.1%. Return metrics include ROE of -36.3% and ROA of -29.4%. Relative to the Manufacturing sector, gross margins are 45.4 percentage points above the sector median of 43%, and ROE of -36.3% compares to a sector median of -2.5%.
The balance sheet reflects a conservatively managed balance sheet with D/E of 23%, revenue growth of -12%. The sector median D/E is 0%, putting OCULAR THERAPEUTIX, INC at higher leverage than the typical peer. Overall balance sheet health is adequate for the current business environment.
Below-average quality (34th percentile) raises durability concerns about the fundamental profile and increases the risk of negative earnings surprises.
Above 50MA
37.18%
Net New Highs
+51081
BEDFORD, Mass., Feb. 24, 2026 (GLOBE NEWSWIRE) -- Ocular Therapeutix, Inc. (NASDAQ: OCUL, “Ocular”), an integrated biopharmaceutical company committed to redefining the retina experience, today announced that the Company will participate in several upcoming investor conferences in March 2026. TD Cowen 46th Annual Health Care Conference:Date: Monday, March 2, 2026Fireside Chat: 9:10 – 9:40 AM ETPresenter: Pravin U. Dugel, MD, Executive Chairman, President and CEOLocation: Boston, MA Jefferies Bio
Ocular Therapeutix (NASDAQ:OCUL) reported positive top-line results from its SOL-1 Phase 3 clinical trial evaluating AXPAXLI (also referred to as OTX-TKI) in wet age-related macular degeneration (wet AMD), highlighting sustained disease control, visual and anatomic outcomes, and a safety profile the
Ocular Therapeutix Inc. (NASDAQ:OCUL) shares are down during Tuesday's premarket session following a significant announcement regarding their Axpaxli treatment for wet age-related macular degeneration (AMD). The stock is trading lower as data did not meet investor expectations. STAT News reported that Axpaxli's durability advantage over the active control was smaller than investors had anticipated, potentially raising questions about its commercial outlook in wet age-related macular degeneration

Ocular Therapeutix (NASDAQ: OCUL) shares surged approximately 21% in premarket trading after reports indicated that Sanofi is preparing a revised and higher takeover bid for the company. Sanofi had previously offered $16 per share in September, which was rejected by Ocular's board. The potential acquisition would give Sanofi exposure to the wet age-related macular degeneration market through Ocular's drug candidate Axpaxli, which is in late-stage development with key clinical data expected in 2026-2027.

Ratings for Ocular Therapeutix (NASDAQ:OCUL) were provided by 6 analysts in the past three months, showcasing a mix of bullish and bearish perspectives. The following table provides a quick overview of their recent ratings, highlighting the changing sentiments over the past 30 days and comparing them to the preceding months. Bullish Somewhat Bullish Indifferent Somewhat Bearish Bearish Total Ratings 3 2 1 0 0 Last 30D 1 0 0 0 0 1M Ago 0 0 0 0 0 2M Ago 2 2 1 0 0 3M Ago 0 0 0 0 0 The 12-month price targets, analyzed by analysts, offer insights with an average target of $16.17, a high estimate of $24.00, and a low estimate of $7.00. A 0.49% drop is evident in the current average compared to the previous average price target of $16.25. Deciphering Analyst Ratings: An In-Depth Analysis The standing of Ocular Therapeutix among financial experts is revealed through an in-depth exploration of recent analyst actions. The summary below outlines key analysts, their recent evaluations, and adjustments to ratings and price targets. Analyst Analyst Firm Action Taken Rating Current Price Target Prior Price Target Yi Chen HC Wainwright & Co. Maintains Buy $14.00 $14.00 Yi Chen HC Wainwright & Co. Lowers Buy $14.00 $16.00 Jonathan Wolleben JMP Securities Lowers Market Outperform $22.00 $24.00 Tara Bancroft TD Cowen Lowers Hold $7.00 $11.00 Yi Chen HC Wainwright & Co. Maintains Buy $16.00 - Jonathan Wolleben JMP Securities Maintains Market Outperform $24.00 - Key Insights: Action Taken: In response to dynamic market conditions and company performance, analysts update their recommendations. Whether they 'Maintain', 'Raise', or 'Lower' their stance, it ...Full story available on Benzinga.com