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Verdict
Quantitative factor alignment verified for current market regime.
Quant Score
Rank
#3606
Positioning
Market Dominance
Manufacturing
Pharmaceutical Products
$768M
Troy E. Wilson
Kura Oncology, Inc. develops medicines for the treatment of cancer in the United States. The company's pipeline consists of small molecule product candidates that target cancer. Its lead product candidates are ziftomenib, a small molecule inhibitor of the menin-Lysine K-specific Methyltransferase 2A protein-protein interaction. tipifarnib, an orally bioavailable inhibitor of farnesyl transferase, is in Phase II clinical trials for the. treatment of solid tumors and hematologic indications.
Headcount
130
HQ Base
SAN DIEGO, California
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| Stock | Rating | Score▼ | Quality | Value | Momentum | P/E | EV/EBITDA | ROE | ROA | Gross Mgn | Op Mgn | Net Mgn | Rev Growth | Div Yield | D/E | Mkt Cap | AUDIT |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
$UL UNILEVER PLC | 78 | 96 | 98 | 59 | - | - | 28.5% | 8.0% | 100.0% | 100.0% | 10.4% | -4.6% | 3.3% | 0.0x | $141.8B | VS | |
$ASML ASML HOLDING NV | 77 | 89 | 86 | 83 | - | - | 46.1% | 16.6% | 51.3% | 31.9% | 26.8% | -4.0% | 1.0% | 25.0x | $272.1B | VS | |
$ESLT ELBIT SYSTEMS LTD | 76 | 81 | 87 | 85 | - | - | 10.3% | 3.1% | 24.1% | 7.2% | 4.7% | 14.3% | 0.8% | 25.0x | $11.4B | VS | |
$MT ArcelorMittal | 75 | 71 | 98 | 85 | - | - | 2.2% | 1.5% | 9.3% | 5.3% | 2.2% | -8.5% | 2.2% | 16.0x | $18.9B | VS | |
$AMAT APPLIED MATERIALS INC /DE | 75 | 85 | 87 | 84 | 20.9x | 13.6x | 35.5% | 19.8% | 48.7% | 29.2% | 24.7% | 4.4% | 0.8% | 32.0x | $181.9B | VS | |
$SIMO Silicon Motion Technology CORP | 75 | 84 | 86 | 85 | - | - | 11.8% | 8.8% | 45.9% | 11.3% | 11.1% | 25.7% | 3.7% | 0.0x | $1.8B | VS | |
$CODA Coda Octopus Group, Inc. | 74 | 83 | 90 | 79 | 16.3x | 11.9x | 7.6% | 7.0% | 66.5% | 17.1% | 15.6% | 39.0% | 0.0% | 0.0x | $115M | VS | |
$GSK GSK plc | 74 | 84 | 90 | 70 | - | - | 22.6% | 4.9% | 71.2% | 12.8% | 9.4% | 1.7% | 5.9% | 124.0x | $72.1B | VS | |
$EFXT Enerflex Ltd. | 74 | 80 | 91 | 83 | - | - | 3.0% | 1.1% | 20.9% | 7.3% | 1.3% | 3.0% | 0.9% | 67.0x | $1.2B | VS | |
$BUD Anheuser-Busch InBev SA/NV | 74 | 84 | 97 | 63 | - | - | 8.2% | 3.5% | 55.3% | 25.9% | 12.4% | 0.7% | 1.7% | 0.0x | $87.0B | VS | |
$KURA Kura Oncology, Inc. | 40 | 34 | 41 | 44 | - | - | -103.9% | -38.8% | 100.0% | -439.8% | -398.9% | - | 0.0% | 168.0x | $768M | ||
| SECTOR BENCH | - | - | - | - | - | 22.3x | 11.5x | -2.5% | -0.1% | 42.5% | 1.3% | -0.2% | 5.9% | 0.0% | 0.2x | - | REF |
Kura Oncology, Inc. (KURA) receives a "Avoid" rating with a composite score of 39.5/100. It ranks #3606 out of 7,333 stocks in our coverage universe and carries a 1-star rating. Ratings are driven by a 6-factor quantitative model measuring quality, value, momentum, investment, stability, and short interest.
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Core pricing power
Operating efficiency
Bottom-line conversion
Equity capital efficiency
Asset base utilization
Financial leverage load
Direct cash return
Troy E. Wilson
Chief Executive Officer
Labor Force
130
34
25
58
Audit Verdict: Lower quality and stability scores may indicate governance concerns.
No recent insider transactions available for KURA
In-line with peers — no strong momentum signal
Fair valuation relative to peers
Weak fundamentals — higher risk of value trap
Average volatility — neutral timing signal
Aggressive spending — empire-building risk, dilutive growth
Below-average composite — caution warranted
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Relative valuation derived from Manufacturing sector benchmarks. Model weights: EV/EBITDA (40%), P/B (35%), P/S (25%). Re-calculated daily.
No analyst ratings for KURA.
View All RatingsInsufficient data for Financial Analysis
| Factor | Global | Sector | Tilt |
|---|---|---|---|
| PROFITABILITY | 34 | 13 | +21ALPHA |
| MOMENTUM | 44 | 27 | +17ALPHA |
| VALUATION | 41 | 19 | +22ALPHA |
| INVESTMENT | 25 | 13 | +12ALPHA |
| STABILITY | 58 | 47 | +11ALPHA |
| SHORT INT | 15 | 1 | +14ALPHA |
Global = full universe. Sector = relative to industry peers. Positive tilt indicates idiosyncratic strength.
ROE proxy -103.9% (sector -2.5%)
GM 100% vs sector 43%, OM -440% vs sector 1%
Capital turnover N/A, R&D intensity 372.2%
Rev growth N/A, 6yr history
Interest coverage -203.6x
Composite assessment of profitability, capital efficiency, and financial strength. Top-tier entities demonstrate sustainable cash flow generation and elite competitive moats.
Profit generated per dollar of shareholder equity
Efficiency of asset utilization
Pricing power and cost efficiency
Core business profitability
Bottom-line profitability
The Quality factor evaluates the persistence and magnitude of realized cash flows. Companies with scores >70 exhibit superior pricing power and structural financial resilience through diverse economic regimes.
Our uncertainty rating tracks the predictability of future cash flows and potential for permanent capital loss. Moderate visibility with standard industry cyclicality.
Our quantitative model flags Kura Oncology, Inc. with an Avoid rating, assigning a composite score of 39.5/100 and 1 out of 5 stars. Ranked #3606 of 7,333 stocks, KURA falls in the bottom tier across key factors. Historically, stocks with this profile have faced elevated risk of underperformance and capital loss.
KURA's quality score of 34/100 is below average, suggesting challenges with profitability or capital efficiency. The company reports a return on equity of -103.9% (sector avg: -2.5%), gross margins of 100.0% (sector avg: 42.5%), net margins of -398.9% (sector avg: -0.2%). Investors should examine whether management is actively addressing these weaknesses or if they reflect structural industry headwinds.
With a value score of 41/100, KURA appears somewhat expensive relative to its fundamentals. Key valuation metrics include a P/B ratio of 3.04x. Investors paying a premium here are likely betting on above-average growth or margin expansion to justify current prices.
Kura Oncology, Inc.'s investment score of 25/100 suggests limited reinvestment activity. Key growth metrics include a return on assets of -38.8% (sector: -0.1%). While this can be positive for mature, cash-generative businesses returning capital to shareholders, it may also signal a lack of growth opportunities or management conservatism.
KURA is currently showing below-average momentum at 44/100, which may indicate weakening institutional interest or negative sentiment shifts. Revenue growth data is not currently available, while a beta of 0.97 reflects its sensitivity to broader market moves. Investors should note that declining momentum can precede further price weakness, though contrarian opportunities sometimes emerge at these levels.
With a stability score of 58/100, KURA exhibits average financial resilience. Key stability metrics include a beta of 0.97 and a debt-to-equity ratio of 168.00x (sector avg: 0.2x). While the balance sheet is not a major concern, the stock is subject to typical market volatility and may experience sharper drawdowns during risk-off episodes.
Kura Oncology, Inc.'s short interest score of 15/100 reveals significant bearish positioning, suggesting institutional investors are actively betting against the stock. Specific risk factors include elevated leverage (D/E: 168.00x), small-cap liquidity risk. At $768M (small-cap), KURA carries meaningful risk and is best suited for investors with high risk tolerance who have thoroughly evaluated the bear thesis.
Kura Oncology, Inc. is a small-cap company in the Manufacturing sector, ranked #0 of 50 in its sector (100th percentile) and #3606 of 7,333 overall (51st percentile). Key comparisons include ROE of -103.9% trailing the -2.5% sector median and operating margins of -439.8% below the 1.3% sector average. This top-quartile standing reflects exceptional competitive strength relative to Manufacturing peers.
While KURA currently exhibits a AVOID profile, superior opportunities exist within the MANUFACTURING sector. Our model identifies several "Strong Buy" candidates with higher quality scores and more attractive valuations among direct industry competitors.
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Improvement in Short Int. (15) would have the largest impact on the composite score.
ROE 4091% ABOVE SECTOR MEDIAN (FAVORABLE)
Gross Margin 135% ABOVE SECTOR MEDIAN (FAVORABLE)
Op. Margin 34194% BELOW SECTOR MEDIAN
AUDIT DATA AS OF SEP 30, 2025 (Q2 FY2025)
We rate Kura Oncology, Inc. (KURA) as Avoid with a composite score of 39.5/100 at a current price of $8.27. The stock falls in the bottom quintile of our universe across key quantitative factors, and the multi-factor weakness suggests a high probability of continued underperformance.
The rating is primarily driven by strength in stability (58th percentile) and momentum (44th percentile), which together account for the majority of the composite score. Offsetting weakness in investment (25th percentile) and quality (34th percentile) tempers our overall conviction. We assign a No Moat rating (23/100), High uncertainty, and Poor capital allocation.
Key items to watch: balance sheet deleveraging progress; the path to profitability. Any material change in these dynamics could warrant a reassessment of our rating. The moat trend is stable, which suggests the competitive landscape is stable for now.
Kura Oncology, Inc. holds a top-quartile position (#0 of 50) within the Manufacturing sector, based on our composite quantitative scoring across quality, value, momentum, and stability factors. The composite score of 39.5/100 places it at rank #3606 in our full 7,333-stock universe. At $768M in market capitalization, Kura Oncology, Inc. is a small-cap player in the Manufacturing space, which limits certain scale advantages but may allow for more agile strategic execution.
Momentum indicators (44th percentile) are neutral regarding the near-term price trend. Revenue growth data is unavailable, limiting our ability to confirm whether momentum is fundamentally supported.
The margin cascade tells an important story: gross margins of 100% (+57.5pp vs sector) narrow to operating margins of -440% (-441.1pp vs sector) and net margins of -398.9%, yielding a gross-to-net conversion rate of -399%. The significant margin erosion from gross to net suggests elevated operating expenses, high interest costs, or other structural drags that warrant monitoring.
At a current price of $8.27, Kura Oncology, Inc. is trading near fair value based on current fundamentals. Our value factor score of 41/100 reflects a composite assessment across multiple valuation metrics including price-to-earnings, price-to-book, EV/EBITDA, and price-to-sales ratios relative to both sector peers and the broader market. Valuation metrics are mixed, with no strong signal of mispricing in either direction.
The stock currently trades at P/B of 3.0x, P/S of 14.7x. We evaluate these multiples in the context of both absolute levels and sector-relative positioning to form our valuation view.
Gross margins of 100% signal strong pricing power and brand/IP advantages — businesses with margins above 40% have historically demonstrated more resilient earnings through economic cycles.
The Avoid rating (composite 39.5/100) reflects multi-factor weakness, and historically, stocks in this scoring range have underperformed the market by a meaningful margin.
Elevated leverage (168% D/E) amplifies downside risk and limits management's financial flexibility in adverse scenarios.
Thin net margins of -398.9% provide limited cushion against cost pressures, competitive pricing, or macroeconomic headwinds — even small changes in costs could swing the company to a loss.
Below-average quality (34th percentile) raises durability concerns about the fundamental profile and increases the risk of negative earnings surprises.
We assign a High uncertainty rating to Kura Oncology, Inc.. Key risk factors include significant leverage (168% debt-to-equity), current negative profitability (net margin -398.9%), weak quality scores (34th percentile). The wide range of potential outcomes widens our fair value estimate and increases the possibility of permanent capital impairment. Investors considering this name should size positions accordingly and demand a meaningful margin of safety before initiating.
Specific risk factors that inform our assessment include: significant leverage (168% debt-to-equity); current negative profitability (net margin -398.9%); weak quality scores (34th percentile); the combination of leverage (168% D/E) and thin margins (-398.9% net) amplifies downside risk. Each of these factors independently widens the distribution of potential outcomes, and in combination they create a risk profile that demands careful position sizing. The stability factor at the 58th percentile and quality factor at the 34th percentile provide a quantitative summary of the overall risk landscape.
Key risk mitigants include: healthy gross margins of 100% provide a buffer against cost pressures. These factors partially offset the identified risks and provide downside protection in adverse scenarios. On balance, the risk-reward profile warrants caution and disciplined position management.
We rate Kura Oncology, Inc.'s capital allocation as Poor. Key concerns include low returns on equity (-103.9%), elevated leverage (168% D/E), negative profitability, weak asset returns (ROA -38.8%). Exemplary capital allocators generate ROE above 20% and maintain conservative leverage — Kura Oncology, Inc. significantly underperforms these benchmarks, raising questions about management's ability to create shareholder value.
Investors should scrutinize management's reinvestment decisions and balance sheet trajectory before committing capital. Poor capital allocation often compounds over time: overlevered balance sheets limit strategic flexibility, while low returns on capital destroy shareholder value. We would need to see sustained improvement in profitability metrics and balance sheet discipline before considering an upgrade.
In summary, Kura Oncology, Inc. receives a Avoid rating with a composite score of 39.5/100 (rank #3606 of 7,333). Our quantitative framework assigns a No Moat (23/100, trend: stable), High uncertainty, and Poor capital allocation. The average factor score across quality, value, momentum, stability, and investment is 40/100.
Our analysis does not support a constructive view on Kura Oncology, Inc. at this time. The combination of limited competitive advantages, high uncertainty, and poor capital allocation suggests unfavorable risk-reward at current levels. We recommend investors avoid new positions and existing holders consider reducing exposure.
Analysis derived from Blank Capital Research quantitative terminal. For informational purposes only. No trade solicitation. Past performance not indicative of future results. Consult a qualified advisor.
We do not assign Kura Oncology, Inc. a meaningful economic moat, scoring 23/100 on our composite assessment. Current fundamentals do not demonstrate the kind of durable competitive advantages — such as superior returns on invested capital, margin superiority, or reinvestment efficiency — that would protect the company from competitive erosion over the long term. The highest-scoring pillar, margin superiority, reached only 10.4/20.
The strongest moat sources are margin superiority (10.4/20) and reinvestment efficiency (7/20). GM 100% vs sector 43%, OM -440% vs sector 1%. Capital turnover N/A, R&D intensity 372.2%. These pillars form the core of Kura Oncology, Inc.'s competitive identity and are the primary drivers of excess returns in our framework.
Areas of relative weakness include growth durability (1.2/20) and economic value creation (2/20). Rev growth N/A, 6yr history. Improvement in these areas could meaningfully widen the moat over time, while deterioration would be an early warning of competitive erosion.
Our moat trend assessment is Stable. Multi-year ROIC and operating margin trajectories show neither meaningful improvement nor deterioration, suggesting the competitive position is steady. We expect Kura Oncology, Inc.'s moat profile to remain largely unchanged absent a material shift in return on capital or industry dynamics.
Key profit drivers include gross margins of 100% providing a solid profitability foundation. The margin cascade from 100% gross to -440% operating to -398.9% net reveals the company's cost structure and reinvestment intensity. Our analysis indicates that profit quality raises some durability concerns, with the quality factor at the 34th percentile.
The margin profile shows gross margins of 100%, operating margins of -440%, net margins of -398.9%. Return metrics include ROE of -103.9% and ROA of -38.8%. Relative to the Manufacturing sector, gross margins are 57.5 percentage points above the sector median of 43%, and ROE of -103.9% compares to a sector median of -2.5%.
The balance sheet reflects high leverage with D/E of 168%, which may limit financial flexibility. The sector median D/E is 0%, putting Kura Oncology, Inc. at higher leverage than the typical peer. Elevated leverage in combination with the current margin profile warrants close monitoring for any deterioration in debt-servicing capacity.
Above 50MA
37.18%
Net New Highs
+51081
Analysts have significantly revised down Kura Oncology, Inc.'s revenue estimates for 2026, alongside an increase in loss per share forecasts. The new consensus predicts revenues of US$139m and losses of US$3.31 per share, reflecting a more conservative outlook. Despite these downgrades, the company's projected revenue growth of 26% annually is still expected to outpace the industry average.

Zacks Research downgraded Kura Oncology (NASDAQ:KURA) from a "hold" to a "strong sell" rating. Despite this downgrade, the broader analyst consensus remains "Moderate Buy" with an average target price of $28.00. The company recently missed EPS estimates and has experienced insider selling, alongside negative financial metrics.

HC Wainwright reaffirmed a "Buy" rating for Kura Oncology (NASDAQ:KURA) with a $40.00 price target, implying a significant upside. Despite missing EPS estimates, Kura Oncology surpassed revenue expectations, and institutional investors have increased their stakes, even as insiders sold shares. Other analysts also maintain positive ratings on the stock, contributing to a consensus "Moderate Buy" rating.
Kura Oncology reported $2.1 million in initial KOMZIFTI sales during its first five weeks of commercial availability and secured $195 million in milestone payments from its collaboration with Kyowa Kirin. The company ended 2025 with $667.3 million in cash and investments and anticipates additional collaboration revenue in 2026. KOMZIFTI, approved for relapsed or refractory AML with an NPM1 mutation, is expected to drive significant revenue growth as Kura expands its U.S. uptake and clinical programs.

Kura Oncology has announced the launch of KOMZIFTI™ (ziftomenib), the first oral menin inhibitor approved by the FDA for adults with relapsed or refractory NPM1-mutated acute myeloid leukemia. Since its commercial release on November 21, 2025, the drug has generated $2.1 million in net product revenue. The company is poised for significant advancements in 2026 with a robust pipeline and strong financial standing, aiming for accelerated U.S. uptake and quarter-over-quarter revenue growth.