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Verdict
Quantitative factor alignment verified for current market regime.
Quant Score
Rank
#4664
Positioning
Market Dominance
Manufacturing
Pharmaceutical Products
$55M
Raymond J. Tesi
INmune Bio, Inc., a clinical-stage immunotherapy company, focuses on developing drugs to reprogram the patient's innate immune system to treat disease. The company develops and commercializes product candidates to treat hematologic malignancies, solid tumors, and chronic inflammation.
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| Stock | Rating | Score▼ | Quality | Value | Momentum | P/E | EV/EBITDA | ROE | ROA | Gross Mgn | Op Mgn | Net Mgn | Rev Growth | Div Yield | D/E | Mkt Cap | AUDIT |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
$UL UNILEVER PLC | 78 | 96 | 98 | 59 | - | - | 28.5% | 8.0% | 100.0% | 100.0% | 10.4% | -4.6% | 3.3% | 0.0x | $141.8B | VS | |
$ASML ASML HOLDING NV | 77 | 89 | 86 | 83 | - | - | 46.1% | 16.6% | 51.3% | 31.9% | 26.8% | -4.0% | 1.0% | 25.0x | $272.1B | VS | |
$ESLT ELBIT SYSTEMS LTD | 76 | 81 | 87 | 85 | - | - | 10.3% | 3.1% | 24.1% | 7.2% | 4.7% | 14.3% | 0.8% | 25.0x | $11.4B | VS | |
$MT ArcelorMittal | 75 | 71 | 98 | 85 | - | - | 2.2% | 1.5% | 9.3% | 5.3% | 2.2% | -8.5% | 2.2% | 16.0x | $18.9B | VS | |
$AMAT APPLIED MATERIALS INC /DE | 75 | 85 | 87 | 84 | 20.9x | 13.6x | 35.5% | 19.8% | 48.7% | 29.2% | 24.7% | 4.4% | 0.8% | 32.0x | $181.9B | VS | |
$SIMO Silicon Motion Technology CORP | 75 | 84 | 86 | 85 | - | - | 11.8% | 8.8% | 45.9% | 11.3% | 11.1% | 25.7% | 3.7% | 0.0x | $1.8B | VS | |
$CODA Coda Octopus Group, Inc. | 74 | 83 | 90 | 79 | 16.3x | 11.9x | 7.6% | 7.0% | 66.5% | 17.1% | 15.6% | 39.0% | 0.0% | 0.0x | $115M | VS | |
$GSK GSK plc | 74 | 84 | 90 | 70 | - | - | 22.6% | 4.9% | 71.2% | 12.8% | 9.4% | 1.7% | 5.9% | 124.0x | $72.1B | VS | |
$EFXT Enerflex Ltd. | 74 | 80 | 91 | 83 | - | - | 3.0% | 1.1% | 20.9% | 7.3% | 1.3% | 3.0% | 0.9% | 67.0x | $1.2B | VS | |
$BUD Anheuser-Busch InBev SA/NV | 74 | 84 | 97 | 63 | - | - | 8.2% | 3.5% | 55.3% | 25.9% | 12.4% | 0.7% | 1.7% | 0.0x | $87.0B | VS | |
$INMB Inmune Bio, Inc. | 28 | 28 | 34 | 11 | - | - | -207.9% | -158.2% | - | -19810.0% | -19478.0% | - | 0.0% | 31.0x | $55M | ||
| SECTOR BENCH | - | - | - | - | - | 22.3x | 11.5x | -2.5% | -0.1% | 42.5% | 1.3% | -0.2% | 5.9% | 0.0% | 0.2x | - | REF |
Inmune Bio, Inc. (INMB) receives a "Avoid" rating with a composite score of 27.5/100. It ranks #4664 out of 7,333 stocks in our coverage universe and carries a 1-star rating. Ratings are driven by a 6-factor quantitative model measuring quality, value, momentum, investment, stability, and short interest.
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Operating efficiency
Bottom-line conversion
Equity capital efficiency
Asset base utilization
Financial leverage load
Direct cash return
Raymond J. Tesi
Chief Executive Officer
Labor Force
10
28
25
25
Audit Verdict: Lower quality and stability scores may indicate governance concerns.
No recent insider transactions available for INMB
Lagging peers — losers tend to keep underperforming
Expensive relative to fundamentals — limited margin of safety
Weak fundamentals — higher risk of value trap
High volatility — wider range of outcomes increases timing risk
Aggressive spending — empire-building risk, dilutive growth
Below-average composite — caution warranted
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Relative valuation derived from Manufacturing sector benchmarks. Model weights: EV/EBITDA (40%), P/B (35%), P/S (25%). Re-calculated daily.
No analyst ratings for INMB.
View All RatingsHigh margin volatility — erratic forensic earnings quality
ROE proxy -207.9% (sector -2.5%)
GM N/A vs sector 43%, OM -19810% vs sector 1%
Capital turnover N/A
Rev growth N/A, 8yr history
Interest coverage N/A
Composite assessment of profitability, capital efficiency, and financial strength. Top-tier entities demonstrate sustainable cash flow generation and elite competitive moats.
Profit generated per dollar of shareholder equity
Efficiency of asset utilization
Pricing power and cost efficiency
Core business profitability
Bottom-line profitability
The Quality factor evaluates the persistence and magnitude of realized cash flows. Companies with scores >70 exhibit superior pricing power and structural financial resilience through diverse economic regimes.
Our uncertainty rating tracks the predictability of future cash flows and potential for permanent capital loss. Moderate visibility with standard industry cyclicality.
Our quantitative model flags Inmune Bio, Inc. with an Avoid rating, assigning a composite score of 27.5/100 and 1 out of 5 stars. Ranked #4664 of 7,333 stocks, INMB falls in the bottom tier across key factors. Historically, stocks with this profile have faced elevated risk of underperformance and capital loss.
INMB's quality score of 28/100 is below average, suggesting challenges with profitability or capital efficiency. The company reports a return on equity of -207.9% (sector avg: -2.5%), net margins of -19478.0% (sector avg: -0.2%). Investors should examine whether management is actively addressing these weaknesses or if they reflect structural industry headwinds.
With a value score of 34/100, INMB appears somewhat expensive relative to its fundamentals. Key valuation metrics include a P/B ratio of 1.37x. Investors paying a premium here are likely betting on above-average growth or margin expansion to justify current prices.
Inmune Bio, Inc.'s investment score of 25/100 suggests limited reinvestment activity. Key growth metrics include a return on assets of -158.2% (sector: -0.1%). While this can be positive for mature, cash-generative businesses returning capital to shareholders, it may also signal a lack of growth opportunities or management conservatism.
Inmune Bio, Inc. is experiencing notably weak momentum with a score of just 11/100. The stock has underperformed its peers and is trending below major moving averages. Revenue growth data is not currently available, while a beta of 1.70 reflects its sensitivity to broader market moves. While deep momentum weakness can occasionally present value opportunities, it often reflects deteriorating fundamentals or structural headwinds that may persist.
INMB's stability score of 25/100 signals elevated volatility and/or leverage concerns. Key stability metrics include a beta of 1.70 and a debt-to-equity ratio of 31.00x (sector avg: 0.2x). Investors should be prepared for wider-than-average price swings and consider position sizing accordingly to manage portfolio risk.
Inmune Bio, Inc.'s short interest score of 18/100 reveals significant bearish positioning, suggesting institutional investors are actively betting against the stock. Specific risk factors include high market sensitivity (beta: 1.70), elevated leverage (D/E: 31.00x), micro-cap liquidity risk. At $55M (micro-cap), INMB carries meaningful risk and is best suited for investors with high risk tolerance who have thoroughly evaluated the bear thesis.
Inmune Bio, Inc. is a micro-cap company in the Manufacturing sector, ranked #0 of 50 in its sector (100th percentile) and #4664 of 7,333 overall (36th percentile). Key comparisons include ROE of -207.9% trailing the -2.5% sector median and operating margins of -19810.0% below the 1.3% sector average. This top-quartile standing reflects exceptional competitive strength relative to Manufacturing peers.
While INMB currently exhibits a AVOID profile, superior opportunities exist within the MANUFACTURING sector. Our model identifies several "Strong Buy" candidates with higher quality scores and more attractive valuations among direct industry competitors.
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Improvement in Momentum (11) would have the largest impact on the composite score.
ROE 8283% ABOVE SECTOR MEDIAN (FAVORABLE)
Op. Margin 1535759% BELOW SECTOR MEDIAN
Debt/Equity 15400% ABOVE SECTOR MEDIAN
AUDIT DATA AS OF SEP 30, 2025 (Q2 FY2025)
We rate Inmune Bio, Inc. (INMB) as Avoid with a composite score of 27.5/100 at a current price of $1.35. The stock falls in the bottom quintile of our universe across key quantitative factors, and the multi-factor weakness suggests a high probability of continued underperformance.
The rating is primarily driven by strength in value (34th percentile) and quality (28th percentile), which together account for the majority of the composite score. Offsetting weakness in momentum (11th percentile) and investment (25th percentile) tempers our overall conviction. We assign a No Moat rating (16/100), Very High uncertainty, and Poor capital allocation.
Key items to watch: momentum to confirm whether the current price trend has legs; the path to profitability. Any material change in these dynamics could warrant a reassessment of our rating. The moat trend is narrowing, which raises the risk of a future downgrade if the trend persists.
Inmune Bio, Inc. holds a top-quartile position (#0 of 50) within the Manufacturing sector, based on our composite quantitative scoring across quality, value, momentum, and stability factors. The composite score of 27.5/100 places it at rank #4664 in our full 7,333-stock universe. At $55M in market capitalization, Inmune Bio, Inc. is a small-cap player in the Manufacturing space, which limits certain scale advantages but may allow for more agile strategic execution.
Momentum indicators (11th percentile) suggest caution regarding the near-term price trend. Revenue growth data is unavailable, limiting our ability to confirm whether momentum is fundamentally supported.
Available margin data shows operating margins of -19810%. Incomplete margin data limits our ability to fully assess the cost structure and margin trajectory, though the available metrics provide a partial view of operating efficiency.
At a current price of $1.35, Inmune Bio, Inc. is trading at a premium to fundamental value. Our value factor score of 34/100 reflects a composite assessment across multiple valuation metrics including price-to-earnings, price-to-book, EV/EBITDA, and price-to-sales ratios relative to both sector peers and the broader market. The premium valuation implies the market is pricing in significant future growth or quality improvements that are not yet fully reflected in current fundamentals.
The stock currently trades at P/B of 1.4x, P/S of 696.5x. We evaluate these multiples in the context of both absolute levels and sector-relative positioning to form our valuation view.
The stock may offer contrarian value if near-term headwinds prove transitory — the current weakness in factor scores may reverse if business fundamentals stabilize.
The Avoid rating (composite 27.5/100) reflects multi-factor weakness, and historically, stocks in this scoring range have underperformed the market by a meaningful margin.
Thin net margins of -19478.0% provide limited cushion against cost pressures, competitive pricing, or macroeconomic headwinds — even small changes in costs could swing the company to a loss.
Weak momentum (11th percentile) suggests institutional selling pressure and unfavorable technical dynamics that may persist.
Below-average quality (28th percentile) raises durability concerns about the fundamental profile and increases the risk of negative earnings surprises.
We assign a Very High uncertainty rating to Inmune Bio, Inc.. The stock exhibits multiple compounding risk factors: elevated market sensitivity (beta of 1.70), current negative profitability (net margin -19478.0%), below-average price stability (25th percentile). The extreme uncertainty around future cash flows makes precise valuation difficult, and the range of outcomes is exceptionally wide. Only investors with high risk tolerance and extended time horizons should consider this name.
Specific risk factors that inform our assessment include: elevated market sensitivity (beta of 1.70); current negative profitability (net margin -19478.0%); below-average price stability (25th percentile); weak quality scores (28th percentile). Each of these factors independently widens the distribution of potential outcomes, and in combination they create a risk profile that demands careful position sizing. The stability factor at the 25th percentile and quality factor at the 28th percentile provide a quantitative summary of the overall risk landscape.
We identify limited risk mitigants at this time, which contributes to our very high uncertainty assessment. Investors should monitor for improvement in balance sheet metrics, margin stability, and business predictability that could warrant a downgrade in our risk assessment over time.
We rate Inmune Bio, Inc.'s capital allocation as Poor. Key concerns include low returns on equity (-207.9%), negative profitability, weak asset returns (ROA -158.2%). Exemplary capital allocators generate ROE above 20% and maintain conservative leverage — Inmune Bio, Inc. significantly underperforms these benchmarks, raising questions about management's ability to create shareholder value.
Investors should scrutinize management's reinvestment decisions and balance sheet trajectory before committing capital. Poor capital allocation often compounds over time: overlevered balance sheets limit strategic flexibility, while low returns on capital destroy shareholder value. We would need to see sustained improvement in profitability metrics and balance sheet discipline before considering an upgrade.
In summary, Inmune Bio, Inc. receives a Avoid rating with a composite score of 27.5/100 (rank #4664 of 7,333). Our quantitative framework assigns a No Moat (16/100, trend: narrowing), Very High uncertainty, and Poor capital allocation. The average factor score across quality, value, momentum, stability, and investment is 25/100.
Our analysis does not support a constructive view on Inmune Bio, Inc. at this time. The combination of limited competitive advantages, very high uncertainty, and poor capital allocation suggests unfavorable risk-reward at current levels. We recommend investors avoid new positions and existing holders consider reducing exposure.
Analysis derived from Blank Capital Research quantitative terminal. For informational purposes only. No trade solicitation. Past performance not indicative of future results. Consult a qualified advisor.
We do not assign Inmune Bio, Inc. a meaningful economic moat, scoring 16/100 on our composite assessment. Current fundamentals do not demonstrate the kind of durable competitive advantages — such as superior returns on invested capital, margin superiority, or reinvestment efficiency — that would protect the company from competitive erosion over the long term. The highest-scoring pillar, margin superiority, reached only 6.5/20.
The strongest moat sources are margin superiority (6.5/20) and financial resilience (5.9/20). GM N/A vs sector 43%, OM -19810% vs sector 1%. Interest coverage N/A. These pillars form the core of Inmune Bio, Inc.'s competitive identity and are the primary drivers of excess returns in our framework.
Areas of relative weakness include economic value creation (0/20) and reinvestment efficiency (0/20). ROE proxy -207.9% (sector -2.5%). Improvement in these areas could meaningfully widen the moat over time, while deterioration would be an early warning of competitive erosion.
Our moat trend assessment is Narrowing. ROIC has declined at ~59.1pp per year, and operating margins show fundamental deterioration. Investors should monitor these indicators closely — a sustained narrowing trend often precedes material downgrades in our moat assessment.
Key profit drivers are not clearly identifiable from current fundamentals. This may reflect a company in transition, a cyclical downturn, or structural challenges in the business model. We assign a quality factor of 28/100 which further underscores our concern regarding earnings sustainability.
The margin profile shows operating margins of -19810%, net margins of -19478.0%. Return metrics include ROE of -207.9% and ROA of -158.2%. Relative to the Manufacturing sector, sector comparison data is limited, and ROE of -207.9% compares to a sector median of -2.5%.
The balance sheet reflects moderate leverage with D/E of 31%. The sector median D/E is 0%, putting Inmune Bio, Inc. at higher leverage than the typical peer. Overall balance sheet health is adequate for the current business environment.
High beta of 1.70 means amplified losses in market selloffs — in a broad market correction, this stock would likely decline more than the index.
Above 50MA
37.18%
Net New Highs
+51081

INmune Bio (NASDAQ: INMB) is set to host a webinar on February 27, 2026, to outline the registrational strategy for its Alzheimer's therapeutic, XPro1595. The discussion will cover Phase 2 MINDFuL trial results, FDA End-of-Phase 2 feedback supporting a biomarker-enriched registrational study, and the company's Phase 3 roadmap, including global partnership plans. This webinar aims to provide clarity on the drug's path to Phase 3 readiness and potential market entry.

INmune Bio (NASDAQ: INMB) has submitted a pre-submission package for its CORDStrom™ therapy to the UK MHRA, a critical step towards marketing authorization for recessive dystrophic epidermolysis bullosa (RDEB), also known as 'butterfly skin' disease. The company reported positive safety and efficacy data from its MissionEB clinical trial and successful commercial pilot manufacturing runs. INmune Bio plans to file a full Marketing Authorization Application with the MHRA by mid-summer 2026, with EU and U.S. submissions targeted for Q4 2026.

INmune Bio (NASDAQ: INMB) CEO David Moss has reviewed the company's 2025 progress and outlined strategic initiatives for 2026, focusing on two key programs: CORDStrom for recessive dystrophic epidermolysis bullosa (RDEB) and XPro (XPro1595) for Alzheimer’s disease. The company plans regulatory submissions for CORDStrom in mid-2026 for the UK and late 2026 for the US, while XPro's Phase 2 trial showed promising biomarker-defined signals for guiding a precision-medicine registrational path. INmune Bio reports $27.7 million in cash and equivalents as of September 30, 2025, expected to fund operations through the end of 2026.
INmune Bio (NASDAQ:INMB) stock plummeted after its Alzheimer's drug, XPro1595, failed to meet the primary cognitive endpoint in a Phase 2 clinical trial. Despite the setback, the company suggested a potential beneficial effect in a subgroup of patients and plans to refine its diagnostic criteria for future studies. The clinical hold on high-dose trials for XPro1595 in Alzheimer's patients remains in place from the FDA.
INmune Bio (NASDAQ: INMB) announced a peer-reviewed overview on mesenchymal stromal cell (MSC) therapies published in Cytotherapy, featuring lead scientist Dr. Nikita M. Patel as a senior author. The company plans to file a Biologics License Application (BLA) and Marketing Authorization Application (MAA) in 2026 for its CORDStrom™ platform, initially targeting Recessive Dystrophic Epidermolysis Bullosa (RDEB). This publication reinforces the scientific foundation for CORDStrom™ and future MSC therapy developments.