DTIL

We rate PRECISION BIOSCIENCES INC (DTIL) as Avoid with a composite score of 28.1/100 at a current price of $4.02. The stock falls in the bottom quintile of our universe across key quantitative factors, and the multi-factor weakness suggests a high probability of continued underperformance.

The rating is primarily driven by strength in stability (56th percentile) and investment (48th percentile), which together account for the majority of the composite score. Offsetting weakness in value (8th percentile) and quality (21th percentile) tempers our overall conviction. We assign a No Moat rating (32/100), High uncertainty, and Poor capital allocation.

Key items to watch: momentum to confirm whether the current price trend has legs; balance sheet deleveraging progress; the path to profitability. Any material change in these dynamics could warrant a reassessment of our rating. The moat trend is stable, which suggests the competitive landscape is stable for now.

PRECISION BIOSCIENCES INC holds a top-quartile position (#0 of 50) within the Manufacturing sector, based on our composite quantitative scoring across quality, value, momentum, and stability factors. The composite score of 28.1/100 places it at rank #4640 in our full 7,333-stock universe. At $65M in market capitalization, PRECISION BIOSCIENCES INC is a small-cap player in the Manufacturing space, which limits certain scale advantages but may allow for more agile strategic execution.

Revenue contraction of -100% combined with momentum at the 21th percentile paints a cautious picture of the near-term business outlook. The market appears to be pricing in continued challenges, and a catalyst for reversal is not clearly visible from current data.

The margin cascade tells an important story: gross margins of 100% (+57.5pp vs sector) narrow to operating margins of -90114% (-90115.7pp vs sector) and net margins of -92977.2%, yielding a gross-to-net conversion rate of -92977%. The significant margin erosion from gross to net suggests elevated operating expenses, high interest costs, or other structural drags that warrant monitoring.

At a current price of $4.02, PRECISION BIOSCIENCES INC is trading at a premium to fundamental value. Our value factor score of 8/100 reflects a composite assessment across multiple valuation metrics including price-to-earnings, price-to-book, EV/EBITDA, and price-to-sales ratios relative to both sector peers and the broader market. The premium valuation implies the market is pricing in significant future growth or quality improvements that are not yet fully reflected in current fundamentals.

The stock currently trades at P/B of 5.5x, P/S of 143.4x. We evaluate these multiples in the context of both absolute levels and sector-relative positioning to form our valuation view.

We assign a High uncertainty rating to PRECISION BIOSCIENCES INC. Key risk factors include significant leverage (462% debt-to-equity), current negative profitability (net margin -92977.2%), weak quality scores (21th percentile). The wide range of potential outcomes widens our fair value estimate and increases the possibility of permanent capital impairment. Investors considering this name should size positions accordingly and demand a meaningful margin of safety before initiating.

Specific risk factors that inform our assessment include: significant leverage (462% debt-to-equity); current negative profitability (net margin -92977.2%); weak quality scores (21th percentile); low beta of 0.64 — while defensive, this may indicate limited upside participation in bull markets. Each of these factors independently widens the distribution of potential outcomes, and in combination they create a risk profile that demands careful position sizing. The stability factor at the 56th percentile and quality factor at the 21th percentile provide a quantitative summary of the overall risk landscape.

Key risk mitigants include: healthy gross margins of 100% provide a buffer against cost pressures. These factors partially offset the identified risks and provide downside protection in adverse scenarios. On balance, the risk-reward profile warrants caution and disciplined position management.

We rate PRECISION BIOSCIENCES INC's capital allocation as Poor. Key concerns include low returns on equity (-494.7%), elevated leverage (462% D/E), negative profitability, weak asset returns (ROA -88.0%). Exemplary capital allocators generate ROE above 20% and maintain conservative leverage — PRECISION BIOSCIENCES INC significantly underperforms these benchmarks, raising questions about management's ability to create shareholder value.

Investors should scrutinize management's reinvestment decisions and balance sheet trajectory before committing capital. Poor capital allocation often compounds over time: overlevered balance sheets limit strategic flexibility, while low returns on capital destroy shareholder value. We would need to see sustained improvement in profitability metrics and balance sheet discipline before considering an upgrade.

In summary, PRECISION BIOSCIENCES INC receives a Avoid rating with a composite score of 28.1/100 (rank #4640 of 7,333). Our quantitative framework assigns a No Moat (32/100, trend: stable), High uncertainty, and Poor capital allocation. The average factor score across quality, value, momentum, stability, and investment is 31/100.

Our analysis does not support a constructive view on PRECISION BIOSCIENCES INC at this time. The combination of limited competitive advantages, high uncertainty, and poor capital allocation suggests unfavorable risk-reward at current levels. We recommend investors avoid new positions and existing holders consider reducing exposure.