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Verdict
Quantitative factor alignment verified for current market regime.
Quant Score
Rank
#579
Positioning
Market Dominance
Manufacturing
Pharmaceutical Products
$1.1B
Joseph J. Ciaffoni
Collegium Pharmaceutical, Inc. develops and commercializes medicines for pain management. Xtampza ER is an abuse-deterrent, extended-release, oral formulation of oxycodone.
Headcount
210
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X-AXIS: EV/EBITDA (LOWER = CHEAPER) | Y-AXIS: ROE (HIGHER = ELITE) | RED CIRCLE = COLL ANALYSIS TARGET
| Stock | Rating | Score▼ | Quality | Value | Momentum | P/E | EV/EBITDA | ROE | ROA | Gross Mgn | Op Mgn | Net Mgn | Rev Growth | Div Yield | D/E | Mkt Cap | AUDIT |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
$UL UNILEVER PLC | 78 | 96 | 98 | 59 | - | - | 28.5% | 8.0% | 100.0% | 100.0% | 10.4% | -4.6% | 3.3% | 0.0x | $141.8B | VS | |
$ASML ASML HOLDING NV | 77 | 89 | 86 | 83 | - | - | 46.1% | 16.6% | 51.3% | 31.9% | 26.8% | -4.0% | 1.0% | 25.0x | $272.1B | VS | |
$ESLT ELBIT SYSTEMS LTD | 76 | 81 | 87 | 85 | - | - | 10.3% | 3.1% | 24.1% | 7.2% | 4.7% | 14.3% | 0.8% | 25.0x | $11.4B | VS | |
$MT ArcelorMittal | 75 | 71 | 98 | 85 | - | - | 2.2% | 1.5% | 9.3% | 5.3% | 2.2% | -8.5% | 2.2% | 16.0x | $18.9B | VS | |
$AMAT APPLIED MATERIALS INC /DE | 75 | 85 | 87 | 84 | 20.9x | 13.6x | 35.5% | 19.8% | 48.7% | 29.2% | 24.7% | 4.4% | 0.8% | 32.0x | $181.9B | VS | |
$SIMO Silicon Motion Technology CORP | 75 | 84 | 86 | 85 | - | - | 11.8% | 8.8% | 45.9% | 11.3% | 11.1% | 25.7% | 3.7% | 0.0x | $1.8B | VS | |
$CODA Coda Octopus Group, Inc. | 74 | 83 | 90 | 79 | 16.3x | 11.9x | 7.6% | 7.0% | 66.5% | 17.1% | 15.6% | 39.0% | 0.0% | 0.0x | $115M | VS | |
$GSK GSK plc | 74 | 84 | 90 | 70 | - | - | 22.6% | 4.9% | 71.2% | 12.8% | 9.4% | 1.7% | 5.9% | 124.0x | $72.1B | VS | |
$EFXT Enerflex Ltd. | 74 | 80 | 91 | 83 | - | - | 3.0% | 1.1% | 20.9% | 7.3% | 1.3% | 3.0% | 0.9% | 67.0x | $1.2B | VS | |
$BUD Anheuser-Busch InBev SA/NV | 74 | 84 | 97 | 63 | - | - | 8.2% | 3.5% | 55.3% | 25.9% | 12.4% | 0.7% | 1.7% | 0.0x | $87.0B | VS | |
$COLL COLLEGIUM PHARMACEUTICAL, INC | 61 | 73 | 90 | 62 | 25.8x | 9.3x | 20.1% | 3.4% | 58.7% | 20.6% | 7.2% | 44.1% | 0.0% | 485.0x | $1.1B | ||
| SECTOR BENCH | - | - | - | - | - | 22.3x | 11.5x | -2.5% | -0.1% | 42.5% | 1.3% | -0.2% | 5.9% | 0.0% | 0.2x | - | REF |
COLLEGIUM PHARMACEUTICAL, INC (COLL) receives a "Hold" rating with a composite score of 61.2/100. It ranks #579 out of 7,333 stocks in our coverage universe and carries a 3-star rating. Ratings are driven by a 6-factor quantitative model measuring quality, value, momentum, investment, stability, and short interest.
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YOY expansion rate
Core pricing power
Operating efficiency
Bottom-line conversion
Equity capital efficiency
Asset base utilization
Financial leverage load
Direct cash return
Joseph J. Ciaffoni
Chief Executive Officer
Labor Force
210
73
24
86
Audit Verdict: Average governance indicators based on financial metrics.
No recent insider transactions available for COLL
HQ Base
Canton, Massachusetts
Outperforming peers — winners tend to keep winning over 3-12 months
Trading at a discount to fundamentals — favorable entry valuation
High profitability & efficiency — strong quality floor supports entry
Low volatility — smoother ride and historically better risk-adjusted returns
Aggressive spending — empire-building risk, dilutive growth
Mid-range overall rating
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Relative valuation derived from Manufacturing sector benchmarks. Model weights: EV/EBITDA (40%), P/B (35%), P/S (25%). Re-calculated daily.
Projection based on user-defined inputs. Re-calculated daily against current market data.
Reverse DCF Framework — Mauboussin Methodology
Institutional-grade Reverse DCF analysis. This model identifies the growth hurdles embedded in current market prices. When implied growth is significantly lower than historical or projected rates, a margin of safety may exist. Re-audited daily.
No analyst ratings for COLL.
View All RatingsConservative accounting — High cash conversion efficiency
High margin volatility — erratic forensic earnings quality
| Factor | Global | Sector | Tilt |
|---|---|---|---|
| PROFITABILITY | 73 | 80 | -7DRAG |
| MOMENTUM | 62 | 57 | +5NEUTRAL |
| VALUATION | 90 | 93 | -3NEUTRAL |
| INVESTMENT | 24 | 11 | +13ALPHA |
| STABILITY | 86 | 90 | -4NEUTRAL |
| SHORT INT | 41 | 35 | +6ALPHA |
Global = full universe. Sector = relative to industry peers. Positive tilt indicates idiosyncratic strength.
ROIC 6.6% vs WACC 6.9% (spread -0.3%)
GM 59% vs sector 43%, OM 21% vs sector 1%
Capital turnover 0.32x
Rev growth 44%, 10yr history
Interest coverage 2.9x, Net debt/EBITDA 10.6x
Composite assessment of profitability, capital efficiency, and financial strength. Top-tier entities demonstrate sustainable cash flow generation and elite competitive moats.
Profit generated per dollar of shareholder equity
Efficiency of asset utilization
Pricing power and cost efficiency
Core business profitability
Bottom-line profitability
The Quality factor evaluates the persistence and magnitude of realized cash flows. Companies with scores >70 exhibit superior pricing power and structural financial resilience through diverse economic regimes.
Our uncertainty rating tracks the predictability of future cash flows and potential for permanent capital loss. Moderate visibility with standard industry cyclicality.
Our model assigns COLLEGIUM PHARMACEUTICAL, INC a Hold rating, with a composite score of 61.2/100 and 3 out of 5 stars. Ranked #579 of 7,333 stocks, COLL presents a mixed quantitative picture — neither compelling enough to initiate new positions nor weak enough to warrant selling. Investors already holding may consider maintaining their position while monitoring for changes in the factor profile.
COLL earns a quality score of 73/100, indicating above-average business quality. The company reports a return on equity of 20.1% (sector avg: -2.5%), gross margins of 58.7% (sector avg: 42.5%), net margins of 7.2% (sector avg: -0.2%). Companies in this tier generally demonstrate consistent profitability and efficient capital deployment, though they may face some competitive pressure.
From a valuation perspective, COLL scores an exceptional 90/100, indicating the stock trades at a deep discount relative to its fundamentals. Key valuation metrics include a P/E ratio of 25.75x, an EV/EBITDA of 9.25x, a P/B ratio of 5.18x. A value score this high suggests the market may be significantly underpricing the company's earnings power, assets, or cash flow generation.
COLLEGIUM PHARMACEUTICAL, INC's investment score of 24/100 suggests limited reinvestment activity. Key growth metrics include revenue growth of 44.1% vs. a sector average of 5.9% and a return on assets of 3.4% (sector: -0.1%). While this can be positive for mature, cash-generative businesses returning capital to shareholders, it may also signal a lack of growth opportunities or management conservatism.
COLL demonstrates moderate momentum with a score of 62/100, suggesting a neutral price trend without strong directional conviction. Revenue growth stands at 44.1% year-over-year, while a beta of 0.48 reflects its sensitivity to broader market moves. Moderate momentum may indicate the stock is consolidating or transitioning between trends, warranting close monitoring of upcoming catalysts.
COLLEGIUM PHARMACEUTICAL, INC earns an excellent stability score of 86/100, reflecting low price volatility and a conservatively managed balance sheet. Key stability metrics include a beta of 0.48 and a debt-to-equity ratio of 485.00x (sector avg: 0.2x). Stocks with this level of stability tend to act as portfolio anchors, providing downside protection during market corrections while still participating in broad market advances.
The short interest score of 41/100 for COLL suggests somewhat elevated bearish positioning by institutional traders. Specific risk factors include elevated leverage (D/E: 485.00x), small-cap liquidity risk. With a $1.1B market cap (small-cap), COLLEGIUM PHARMACEUTICAL, INC may experience above-average volatility. Investors should consider whether the short thesis has merit or if it creates a potential short-squeeze opportunity.
COLLEGIUM PHARMACEUTICAL, INC is a small-cap company in the Manufacturing sector, ranked #0 of 50 in its sector (100th percentile) and #579 of 7,333 overall (92nd percentile). Key comparisons include ROE of 20.1% exceeding the -2.5% sector median and operating margins of 20.6% above the 1.3% sector average. This top-quartile standing reflects exceptional competitive strength relative to Manufacturing peers.
While COLL currently exhibits a HOLD profile, superior opportunities exist within the MANUFACTURING sector. Our model identifies several "Strong Buy" candidates with higher quality scores and more attractive valuations among direct industry competitors.
View Top Manufacturing Alpha →Quant Factor Profile
Key factor gap
Value (90) vs Investment (24) — closing this gap could shift the rating.
EV/EBITDA 19% BELOW SECTOR MEDIAN (FAVORABLE)
ROE 910% BELOW SECTOR MEDIAN
Gross Margin 38% ABOVE SECTOR MEDIAN (FAVORABLE)
AUDIT DATA AS OF SEP 30, 2025 (Q2 FY2025)
We rate COLLEGIUM PHARMACEUTICAL, INC (COLL) as a Hold with a composite score of 61.2/100 at a current price of $45.19. The stock presents a mixed quantitative picture — neither compelling enough to warrant new accumulation nor weak enough to justify selling for existing holders. Our factors are split, and the overall profile suggests patience is warranted.
The rating is primarily driven by strength in value (90th percentile) and stability (86th percentile), which together account for the majority of the composite score. Offsetting weakness in investment (24th percentile) and momentum (62th percentile) tempers our overall conviction. We assign a Narrow Moat rating (42/100), Medium uncertainty, and Poor capital allocation.
Key items to watch: balance sheet deleveraging progress; sustainability of the current growth rate. Any material change in these dynamics could warrant a reassessment of our rating. The moat trend is stable, which suggests the competitive landscape is stable for now.
COLLEGIUM PHARMACEUTICAL, INC holds a top-quartile position (#0 of 50) within the Manufacturing sector, based on our composite quantitative scoring across quality, value, momentum, and stability factors. The composite score of 61.2/100 places it at rank #579 in our full 7,333-stock universe. At $1.1B in market capitalization, COLLEGIUM PHARMACEUTICAL, INC is a small-cap player in the Manufacturing space, which limits certain scale advantages but may allow for more agile strategic execution.
The near-term outlook is constructive, with revenue growing at 44% and momentum in the 62th percentile confirming positive market sentiment and institutional accumulation. The combination of strong top-line growth and favorable price dynamics suggests the company is executing well on its growth strategy. Investment factor at the 24th percentile indicates reinvestment patterns that investors should monitor for sustainability.
The margin cascade tells an important story: gross margins of 59% (+16.2pp vs sector) narrow to operating margins of 21% (+19.3pp vs sector) and net margins of 7.2%, yielding a gross-to-net conversion rate of 12%. The significant margin erosion from gross to net suggests elevated operating expenses, high interest costs, or other structural drags that warrant monitoring.
At a current price of $45.19, COLLEGIUM PHARMACEUTICAL, INC appears undervalued relative to its fundamentals. Our value factor score of 90/100 reflects a composite assessment across multiple valuation metrics including price-to-earnings, price-to-book, EV/EBITDA, and price-to-sales ratios relative to both sector peers and the broader market. The stock screens as attractively priced on a majority of these measures, suggesting the market may be underappreciating the underlying fundamentals.
The stock currently trades at a P/E of 25.8x (roughly in line with the sector median of 22.3x), EV/EBITDA of 9.3x (near the sector median), P/B of 5.2x, P/S of 1.9x. The above-sector P/E multiple suggests the market is pricing in superior growth or quality, which our analysis partially supports given strong quality metrics.
Gross margins of 59% signal strong pricing power and brand/IP advantages — businesses with margins above 40% have historically demonstrated more resilient earnings through economic cycles.
Returns on equity of 20.1% exceed the cost of equity for most companies, indicating genuine shareholder value creation and a reinvestment engine that compounds wealth over time.
Revenue growth of 44% confirms the business is expanding its addressable market — growth at this level typically supports multiple expansion and attracts institutional capital.
A value factor score of 90/100 suggests the market is underpricing these fundamentals, creating a potential margin of safety for new investors.
Elevated leverage (485% D/E) amplifies downside risk and limits management's financial flexibility in adverse scenarios.
We assign a Medium uncertainty rating to COLLEGIUM PHARMACEUTICAL, INC. The stock presents a balanced risk profile: significant leverage (485% debt-to-equity) and low beta of 0.48 — while defensive, this may indicate limited upside participation in bull markets. While not risk-free, the core business fundamentals are adequate to withstand moderate economic stress, and the range of potential outcomes around our fair value estimate is manageable.
Specific risk factors that inform our assessment include: significant leverage (485% debt-to-equity); low beta of 0.48 — while defensive, this may indicate limited upside participation in bull markets. Each of these factors independently widens the distribution of potential outcomes, and in combination they create a risk profile that demands careful position sizing. The stability factor at the 86th percentile and quality factor at the 73th percentile provide a quantitative summary of the overall risk landscape.
Key risk mitigants include: healthy gross margins of 59% provide a buffer against cost pressures; above-average stability (86th percentile) suggests predictable business dynamics. These factors partially offset the identified risks and provide downside protection in adverse scenarios. On balance, the risk-reward profile is favorable for long-term investors.
We rate COLLEGIUM PHARMACEUTICAL, INC's capital allocation as Poor. Key concerns include elevated leverage (485% D/E). Exemplary capital allocators generate ROE above 20% and maintain conservative leverage — COLLEGIUM PHARMACEUTICAL, INC significantly underperforms these benchmarks, raising questions about management's ability to create shareholder value.
Investors should scrutinize management's reinvestment decisions and balance sheet trajectory before committing capital. Poor capital allocation often compounds over time: overlevered balance sheets limit strategic flexibility, while low returns on capital destroy shareholder value. We would need to see sustained improvement in profitability metrics and balance sheet discipline before considering an upgrade.
In summary, COLLEGIUM PHARMACEUTICAL, INC receives a Hold rating with a composite score of 61.2/100 (rank #579 of 7,333). Our quantitative framework assigns a Narrow Moat (42/100, trend: stable), Medium uncertainty, and Poor capital allocation. The average factor score across quality, value, momentum, stability, and investment is 67/100.
Our analysis supports a neutral stance on COLLEGIUM PHARMACEUTICAL, INC. While the quantitative profile is not weak enough to warrant selling, it lacks the multi-factor strength required for a buy recommendation. Existing holders should maintain positions and monitor for catalysts — either fundamental improvement or valuation compression — that would shift the risk-reward balance.
Analysis derived from Blank Capital Research quantitative terminal. For informational purposes only. No trade solicitation. Past performance not indicative of future results. Consult a qualified advisor.
We assign COLLEGIUM PHARMACEUTICAL, INC a Narrow Moat rating with a composite moat score of 42/100. The ROIC-WACC spread of -0.3% is the primary signal of economic value creation. The company possesses identifiable competitive advantages, though they are less entrenched than those of wide-moat peers. Our analysis indicates that COLLEGIUM PHARMACEUTICAL, INC can sustain above-average returns on invested capital for at least 10 years, with the strongest contributor being growth durability at 17.2/20.
The strongest moat sources are growth durability (17.2/20) and margin superiority (15.7/20). Rev growth 44%, 10yr history. GM 59% vs sector 43%, OM 21% vs sector 1%. These pillars form the core of COLLEGIUM PHARMACEUTICAL, INC's competitive identity and are the primary drivers of excess returns in our framework.
Areas of relative weakness include reinvestment efficiency (0/20) and financial resilience (3.1/20). Capital turnover 0.32x. Improvement in these areas could meaningfully widen the moat over time, while deterioration would be an early warning of competitive erosion.
Our moat trend assessment is Stable. Multi-year ROIC and operating margin trajectories show neither meaningful improvement nor deterioration, suggesting the competitive position is steady. We expect COLLEGIUM PHARMACEUTICAL, INC's moat profile to remain largely unchanged absent a material shift in return on capital or industry dynamics.
Key profit drivers include gross margins of 59% providing a solid profitability foundation, operating margins of 21% reflecting effective cost management, robust top-line growth of 44% expanding the revenue base. The margin cascade from 59% gross to 21% operating to 7.2% net reveals the company's cost structure and reinvestment intensity. Our analysis indicates that the profit engine is high-quality and likely sustainable, with the quality factor at the 73th percentile.
The margin profile shows gross margins of 59%, operating margins of 21%, net margins of 7.2%. Return metrics include ROE of 20.1% and ROA of 3.4%. Relative to the Manufacturing sector, gross margins are 16.2 percentage points above the sector median of 43%, and ROE of 20.1% compares to a sector median of -2.5%.
The balance sheet reflects high leverage with D/E of 485%, which may limit financial flexibility, revenue growth of 44%. The sector median D/E is 0%, putting COLLEGIUM PHARMACEUTICAL, INC at higher leverage than the typical peer. Elevated leverage in combination with the current margin profile warrants close monitoring for any deterioration in debt-servicing capacity.

About COLLEGIUM PHARMACEUTICAL Collegium Pharmaceutical, Inc., a specialty pharmaceutical company, develops and commercializes medicines for pain management. Its portfolio includes Xtampza ER, an abuse-deterrent, extended-release, oral formulation of oxycodone; Nucynta ER and Nucynta IR, which are extended-release and immediate-release formulations of tapentadol; and Xtampza ER for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment. The company w

Truist Securities has increased its price target for Collegium Pharmaceutical (NASDAQ:COLL) to $58.00 from $55.00, reiterating a Buy rating. This adjustment follows positive meetings with Collegium management concerning Jornay PM's growth and the opioid market, with analysts noting greater durability in Collegium's pain franchise than market expectations. Additionally, Collegium recently closed a new $980 million syndicated credit facility, enhancing its financial flexibility.

Versor Investments LP has acquired a new position in Collegium Pharmaceutical, Inc. (NASDAQ:COLL), purchasing 38,201 shares valued at approximately $1.34 million. This move represents about 0.12% ownership in the company. Concurrently, several insiders, including EVP Scott Dreyer and Director Rita J. Balice-Gordon, have sold shares, while analysts maintain a "Moderate Buy" consensus rating with an average target price of $52.80.

Collegium Pharmaceutical (NASDAQ:COLL) has received an average rating of "Moderate Buy" from seven brokerages, with five recommending a "buy" and two a "hold." The average one-year target price among analysts is $52.80, and several firms recently raised their price targets. The company recently beat quarterly EPS and revenue estimates, though revenue was down year-over-year.

Collegium Pharmaceutical Inc (NASDAQ:COLL) is highlighted as a strong value investing opportunity due to its high earnings and exceptionally low valuation. Despite some financial concerns like a high debt-to-equity ratio and a non-existent dividend, its robust earnings scores and cash flow generation suggest it may offer a "margin of safety" for investors willing to look past its average growth outlook. The article advises further research for those interested in undervalued stocks.
Above 50MA
37.18%
Net New Highs
+51081