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Verdict
Quantitative factor alignment verified for current market regime.
Quant Score
Rank
#1494
Positioning
Market Dominance
Manufacturing
Pharmaceutical Products
$10.4B
Jean-Jacques Bienaimé
BioMarin Pharmaceutical Inc. develops and commercializes therapies for people with serious and life-threatening rare diseases and medical conditions. Vimizim, an enzyme replacement therapy for the treatment of mucopolysaccharidosis IV type A, a lysosomal storage disorder; Naglazyme, a recombinant form of N-acetylgalactosamine 4-sulfatase for patients with MPS VI; and Kuvan, a proprietary synthetic oral form of 6R-BH4 that is used to treat patients with phenylketonuria (PKU), an inherited metabolic disease.
Headcount
3.1K
HQ Base
Novato, California
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X-AXIS: EV/EBITDA (LOWER = CHEAPER) | Y-AXIS: ROE (HIGHER = ELITE) | RED CIRCLE = BMRN ANALYSIS TARGET
| Stock | Rating | Score▼ | Quality | Value | Momentum | P/E | EV/EBITDA | ROE | ROA | Gross Mgn | Op Mgn | Net Mgn | Rev Growth | Div Yield | D/E | Mkt Cap | AUDIT |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
$UL UNILEVER PLC | 78 | 96 | 98 | 59 | - | - | 28.5% | 8.0% | 100.0% | 100.0% | 10.4% | -4.6% | 3.3% | 0.0x | $141.8B | VS | |
$ASML ASML HOLDING NV | 77 | 89 | 86 | 83 | - | - | 46.1% | 16.6% | 51.3% | 31.9% | 26.8% | -4.0% | 1.0% | 25.0x | $272.1B | VS | |
$ESLT ELBIT SYSTEMS LTD | 76 | 81 | 87 | 85 | - | - | 10.3% | 3.1% | 24.1% | 7.2% | 4.7% | 14.3% | 0.8% | 25.0x | $11.4B | VS | |
$MT ArcelorMittal | 75 | 71 | 98 | 85 | - | - | 2.2% | 1.5% | 9.3% | 5.3% | 2.2% | -8.5% | 2.2% | 16.0x | $18.9B | VS | |
$AMAT APPLIED MATERIALS INC /DE | 75 | 85 | 87 | 84 | 20.9x | 13.6x | 35.5% | 19.8% | 48.7% | 29.2% | 24.7% | 4.4% | 0.8% | 32.0x | $181.9B | VS | |
$SIMO Silicon Motion Technology CORP | 75 | 84 | 86 | 85 | - | - | 11.8% | 8.8% | 45.9% | 11.3% | 11.1% | 25.7% | 3.7% | 0.0x | $1.8B | VS | |
$CODA Coda Octopus Group, Inc. | 74 | 83 | 90 | 79 | 16.3x | 11.9x | 7.6% | 7.0% | 66.5% | 17.1% | 15.6% | 39.0% | 0.0% | 0.0x | $115M | VS | |
$GSK GSK plc | 74 | 84 | 90 | 70 | - | - | 22.6% | 4.9% | 71.2% | 12.8% | 9.4% | 1.7% | 5.9% | 124.0x | $72.1B | VS | |
$EFXT Enerflex Ltd. | 74 | 80 | 91 | 83 | - | - | 3.0% | 1.1% | 20.9% | 7.3% | 1.3% | 3.0% | 0.9% | 67.0x | $1.2B | VS | |
$BUD Anheuser-Busch InBev SA/NV | 74 | 84 | 97 | 63 | - | - | 8.2% | 3.5% | 55.3% | 25.9% | 12.4% | 0.7% | 1.7% | 0.0x | $87.0B | VS | |
$BMRN BIOMARIN PHARMACEUTICAL INC | 53 | 54 | 49 | 44 | 24.6x | 21.7x | 8.3% | 6.6% | 79.5% | 18.2% | 16.1% | 9.0% | 0.0% | 26.0x | $10.4B | ||
| SECTOR BENCH | - | - | - | - | - | 22.3x | 11.5x | -2.5% | -0.1% | 42.5% | 1.3% | -0.2% | 5.9% | 0.0% | 0.2x | - | REF |
BIOMARIN PHARMACEUTICAL INC (BMRN) receives a "Hold" rating with a composite score of 53.3/100. It ranks #1494 out of 7,333 stocks in our coverage universe and carries a 3-star rating. Ratings are driven by a 6-factor quantitative model measuring quality, value, momentum, investment, stability, and short interest.
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YOY expansion rate
Core pricing power
Operating efficiency
Bottom-line conversion
Equity capital efficiency
Asset base utilization
Financial leverage load
Direct cash return
Jean-Jacques Bienaimé
Chief Executive Officer
Labor Force
3,080
54
44
84
Audit Verdict: Average governance indicators based on financial metrics.
No recent insider transactions available for BMRN
In-line with peers — no strong momentum signal
Fair valuation relative to peers
Average quality profile
Low volatility — smoother ride and historically better risk-adjusted returns
Moderate investment profile
Mid-range overall rating
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Relative valuation derived from Manufacturing sector benchmarks. Model weights: EV/EBITDA (40%), P/B (35%), P/S (25%). Re-calculated daily.
Projection based on user-defined inputs. Re-calculated daily against current market data.
Reverse DCF Framework — Mauboussin Methodology
Institutional-grade Reverse DCF analysis. This model identifies the growth hurdles embedded in current market prices. When implied growth is significantly lower than historical or projected rates, a margin of safety may exist. Re-audited daily.
No analyst ratings for BMRN.
View All RatingsMaterial decline in asset turnover efficiency detected
High margin volatility — erratic forensic earnings quality
| Factor | Global | Sector | Tilt |
|---|---|---|---|
| PROFITABILITY | 54 | 42 | +12ALPHA |
| MOMENTUM | 44 | 27 | +17ALPHA |
| VALUATION | 49 | 28 | +21ALPHA |
| INVESTMENT | 44 | 81 | -37DRAG |
| STABILITY | 84 | 87 | -3NEUTRAL |
| SHORT INT | 38 | 30 | +8ALPHA |
Global = full universe. Sector = relative to industry peers. Positive tilt indicates idiosyncratic strength.
ROE proxy 8.3% (sector -2.5%)
GM 80% vs sector 43%, OM 18% vs sector 1%
Capital turnover N/A, R&D intensity 31.1%
Rev growth 9%, 10yr history
Interest coverage -18.1x
Composite assessment of profitability, capital efficiency, and financial strength. Top-tier entities demonstrate sustainable cash flow generation and elite competitive moats.
Profit generated per dollar of shareholder equity
Efficiency of asset utilization
Pricing power and cost efficiency
Core business profitability
Bottom-line profitability
The Quality factor evaluates the persistence and magnitude of realized cash flows. Companies with scores >70 exhibit superior pricing power and structural financial resilience through diverse economic regimes.
Our uncertainty rating tracks the predictability of future cash flows and potential for permanent capital loss. Moderate visibility with standard industry cyclicality.
Our model assigns BIOMARIN PHARMACEUTICAL INC a Hold rating, with a composite score of 53.3/100 and 3 out of 5 stars. Ranked #1494 of 7,333 stocks, BMRN presents a mixed quantitative picture — neither compelling enough to initiate new positions nor weak enough to warrant selling. Investors already holding may consider maintaining their position while monitoring for changes in the factor profile.
With a quality score of 54/100, BMRN shows adequate but unremarkable business quality. The company reports a return on equity of 8.3% (sector avg: -2.5%), gross margins of 79.5% (sector avg: 42.5%), net margins of 16.1% (sector avg: -0.2%). This suggests the company generates acceptable returns but may lack the competitive positioning or operational efficiency to stand out from peers.
With a value score of 49/100, BMRN appears somewhat expensive relative to its fundamentals. Key valuation metrics include a P/E ratio of 24.55x, an EV/EBITDA of 21.67x, a P/B ratio of 2.03x. Investors paying a premium here are likely betting on above-average growth or margin expansion to justify current prices.
With an investment score of 44/100, BMRN exhibits moderate growth-oriented spending. Key growth metrics include revenue growth of 9.0% vs. a sector average of 5.9% and a return on assets of 6.6% (sector: -0.1%). The company appears to be balancing growth investments with capital returns, though the pace of investment may not be enough to accelerate top-line growth meaningfully.
BMRN is currently showing below-average momentum at 44/100, which may indicate weakening institutional interest or negative sentiment shifts. Revenue growth stands at 9.0% year-over-year, while a beta of 0.75 reflects its sensitivity to broader market moves. Investors should note that declining momentum can precede further price weakness, though contrarian opportunities sometimes emerge at these levels.
BMRN shows good financial stability with a score of 84/100. Key stability metrics include a beta of 0.75 and a debt-to-equity ratio of 26.00x (sector avg: 0.2x). This suggests manageable leverage and moderate price volatility, making it appropriate for investors seeking a balance between growth potential and capital preservation.
BIOMARIN PHARMACEUTICAL INC's short interest score of 38/100 reveals significant bearish positioning, suggesting institutional investors are actively betting against the stock. Specific risk factors include elevated leverage (D/E: 26.00x). At $10.4B (large-cap), BMRN carries meaningful risk and is best suited for investors with high risk tolerance who have thoroughly evaluated the bear thesis.
BIOMARIN PHARMACEUTICAL INC is a large-cap company in the Manufacturing sector, ranked #0 of 50 in its sector (100th percentile) and #1494 of 7,333 overall (80th percentile). Key comparisons include ROE of 8.3% exceeding the -2.5% sector median and operating margins of 18.2% above the 1.3% sector average. This top-quartile standing reflects exceptional competitive strength relative to Manufacturing peers.
While BMRN currently exhibits a HOLD profile, superior opportunities exist within the MANUFACTURING sector. Our model identifies several "Strong Buy" candidates with higher quality scores and more attractive valuations among direct industry competitors.
View Top Manufacturing Alpha →Quant Factor Profile
Key factor gap
Stability (84) vs Short Int. (38) — closing this gap could shift the rating.
EV/EBITDA 89% ABOVE SECTOR MEDIAN
ROE 434% BELOW SECTOR MEDIAN
Gross Margin 87% ABOVE SECTOR MEDIAN (FAVORABLE)
AUDIT DATA AS OF SEP 30, 2025 (Q2 FY2025)
We rate BIOMARIN PHARMACEUTICAL INC (BMRN) as a Hold with a composite score of 53.3/100 at a current price of $62.61. The stock presents a mixed quantitative picture — neither compelling enough to warrant new accumulation nor weak enough to justify selling for existing holders. Our factors are split, and the overall profile suggests patience is warranted.
The rating is primarily driven by strength in stability (84th percentile) and quality (54th percentile), which together account for the majority of the composite score. All factors score above the 40th percentile, indicating no material weakness in the quantitative profile. We assign a Narrow Moat rating (51/100), Low uncertainty, and Standard capital allocation.
Key items to watch: quarterly earnings execution and sector-level competitive dynamics. Any material change in these dynamics could warrant a reassessment of our rating. The moat trend is stable, which suggests the competitive landscape is stable for now.
BIOMARIN PHARMACEUTICAL INC holds a top-quartile position (#0 of 50) within the Manufacturing sector, based on our composite quantitative scoring across quality, value, momentum, and stability factors. The composite score of 53.3/100 places it at rank #1494 in our full 7,333-stock universe. With a $10.4B market capitalization, BIOMARIN PHARMACEUTICAL INC operates at meaningful scale within the Manufacturing sector, providing competitive advantages in distribution, procurement, and customer reach.
Revenue is growing at 9%, though momentum at the 44th percentile suggests the market has not yet fully recognized this trajectory. This potential disconnect between fundamental improvement and market recognition could represent an opportunity for patient investors if the growth trend persists.
The margin cascade tells an important story: gross margins of 80% (+37.0pp vs sector) narrow to operating margins of 18% (+16.9pp vs sector) and net margins of 16.1%, yielding a gross-to-net conversion rate of 20%. This conversion rate is typical for the sector, suggesting a standard cost structure without notable efficiency advantages or disadvantages.
At a current price of $62.61, BIOMARIN PHARMACEUTICAL INC is trading near fair value based on current fundamentals. Our value factor score of 49/100 reflects a composite assessment across multiple valuation metrics including price-to-earnings, price-to-book, EV/EBITDA, and price-to-sales ratios relative to both sector peers and the broader market. Valuation metrics are mixed, with no strong signal of mispricing in either direction.
The stock currently trades at a P/E of 24.6x (roughly in line with the sector median of 22.3x), EV/EBITDA of 21.7x (at a premium), P/B of 2.0x, P/S of 4.0x. The above-sector P/E multiple suggests the market is pricing in superior growth or quality, which our analysis finds only partially justified by current fundamentals.
Gross margins of 80% signal strong pricing power and brand/IP advantages — businesses with margins above 40% have historically demonstrated more resilient earnings through economic cycles.
A conservative balance sheet (26% D/E) provides financial flexibility for acquisitions, buybacks, or weathering economic downturns without dilution.
Even high-quality stocks face risks from valuation compression, competitive disruption, or macro shocks that are difficult to quantify in advance.
We assign a Low uncertainty rating to BIOMARIN PHARMACEUTICAL INC. The company exhibits strong financial stability with a beta of 0.75, conservative leverage (26% D/E), and a stability factor in the 84th percentile. The predictable nature of the business model and solid financial position reduce the range of potential outcomes, giving us confidence in our fair value estimate.
We identify no major risk factors at this time. The company's stability factor sits at the 84th percentile with quality at the 54th percentile, both of which support our low-risk assessment. The absence of material leverage, profitability, or volatility concerns reduces the likelihood of a permanent capital loss scenario.
Key risk mitigants include: healthy gross margins of 80% provide a buffer against cost pressures; conservative leverage (26% D/E) limits balance sheet risk; above-average stability (84th percentile) suggests predictable business dynamics. These factors partially offset the identified risks and provide downside protection in adverse scenarios. On balance, the risk-reward profile is favorable for long-term investors.
We rate BIOMARIN PHARMACEUTICAL INC's capital allocation as Standard. Management has shown adequate — though not exceptional — stewardship of shareholder capital. Returns on equity stand at 8.3%, and the balance sheet is managed within acceptable parameters (D/E: 26%). Exemplary allocators typically sustain ROE above 20% and D/E below 50%; BIOMARIN PHARMACEUTICAL INC falls short on at least one dimension.
There is room for improvement in optimizing the capital structure or enhancing shareholder returns. Absent a dividend, the overall capital allocation framework would benefit from either higher reinvestment returns, improved balance sheet efficiency, or increased shareholder distributions. We will monitor for signs of strategic improvement that could warrant an upgrade.
In summary, BIOMARIN PHARMACEUTICAL INC receives a Hold rating with a composite score of 53.3/100 (rank #1494 of 7,333). Our quantitative framework assigns a Narrow Moat (51/100, trend: stable), Low uncertainty, and Standard capital allocation. The average factor score across quality, value, momentum, stability, and investment is 55/100.
Our analysis supports a neutral stance on BIOMARIN PHARMACEUTICAL INC. While the quantitative profile is not weak enough to warrant selling, it lacks the multi-factor strength required for a buy recommendation. Existing holders should maintain positions and monitor for catalysts — either fundamental improvement or valuation compression — that would shift the risk-reward balance.
Analysis derived from Blank Capital Research quantitative terminal. For informational purposes only. No trade solicitation. Past performance not indicative of future results. Consult a qualified advisor.
We assign BIOMARIN PHARMACEUTICAL INC a Narrow Moat rating with a composite moat score of 51/100. The company possesses identifiable competitive advantages, though they are less entrenched than those of wide-moat peers. Our analysis indicates that BIOMARIN PHARMACEUTICAL INC can sustain above-average returns on invested capital for at least 10 years, with the strongest contributor being margin superiority at 18.9/20.
The strongest moat sources are margin superiority (18.9/20) and growth durability (14.9/20). GM 80% vs sector 43%, OM 18% vs sector 1%. Rev growth 9%, 10yr history. These pillars form the core of BIOMARIN PHARMACEUTICAL INC's competitive identity and are the primary drivers of excess returns in our framework.
Areas of relative weakness include economic value creation (4/20) and financial resilience (6.1/20). ROE proxy 8.3% (sector -2.5%). Improvement in these areas could meaningfully widen the moat over time, while deterioration would be an early warning of competitive erosion.
Our moat trend assessment is Stable. Multi-year ROIC and operating margin trajectories show neither meaningful improvement nor deterioration, suggesting the competitive position is steady. We expect BIOMARIN PHARMACEUTICAL INC's moat profile to remain largely unchanged absent a material shift in return on capital or industry dynamics.
Key profit drivers include gross margins of 80% providing a solid profitability foundation, operating margins of 18% reflecting effective cost management, moderate revenue growth of 9%. The margin cascade from 80% gross to 18% operating to 16.1% net reveals the company's cost structure and reinvestment intensity. Our analysis indicates that profit quality is adequate though not exceptional, with the quality factor at the 54th percentile.
The margin profile shows gross margins of 80%, operating margins of 18%, net margins of 16.1%. Return metrics include ROE of 8.3% and ROA of 6.6%. Relative to the Manufacturing sector, gross margins are 37.0 percentage points above the sector median of 43%, and ROE of 8.3% compares to a sector median of -2.5%.
The balance sheet reflects a conservatively managed balance sheet with D/E of 26%, revenue growth of 9%. The sector median D/E is 0%, putting BIOMARIN PHARMACEUTICAL INC at higher leverage than the typical peer. The combination of low leverage and healthy profitability provides significant financial resilience and strategic optionality.
Above 50MA
37.18%
Net New Highs
+51081

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BioMarin Pharmaceutical Inc. (NASDAQ: BMRN) today announced management will participate in four upcoming investor conferences in March.
BioMarin Pharmaceutical Inc (BMRN) reports a 13% revenue increase in 2025, driven by strong performance in Voxzogo and enzyme therapies, while navigating market challenges and strategic expansions.
BioMarin (BMRN) Q4 2025 earnings call recap: revenue growth, Voxzogo outlook, Amicus/Inozyme deals, and 2026 guidance.
BioMarin Pharmaceutical Inc. has reported its fourth quarter and full-year 2025 results, with Q4 revenue rising to US$874.57 million and full-year revenue to US$3.22 billion, while the quarter shifted to a net loss of US$46.57 million and full-year net income eased to US$348.9 million. The combination of higher sales but weaker quarterly profitability, alongside fresh debt financing to support the pending Amicus Therapeutics acquisition and new conditional approval for VOXZOGO in Canada,...