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Verdict
Quantitative factor alignment verified for current market regime.
Quant Score
Rank
#4098
Positioning
Market Dominance
Manufacturing
Pharmaceutical Products
$1.5B
Ramy Farid
Schrödinger, Inc. provides physics-based software platform that enables discovery of novel molecules for drug development and materials applications. The Software segment is focused on selling its software for drug discovery in the life sciences industry. The Drug Discovery segment focuses on building a portfolio of preclinical and clinical programs, internally and through collaborations.
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| Stock | Rating | Score▼ | Quality | Value | Momentum | P/E | EV/EBITDA | ROE | ROA | Gross Mgn | Op Mgn | Net Mgn | Rev Growth | Div Yield | D/E | Mkt Cap | AUDIT |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
$UL UNILEVER PLC | 78 | 96 | 98 | 59 | - | - | - | - | - | - | - | - | - | - | $0 | VS | |
$ASML ASML HOLDING NV | 77 | 89 | 86 | 83 | - | - | - | - | - | - | - | - | - | - | $0 | VS | |
$ESLT ELBIT SYSTEMS LTD | 76 | 81 | 87 | 85 | - | - | - | - | - | - | - | - | - | - | $0 | VS | |
$MT ArcelorMittal | 75 | 71 | 98 | 85 | - | - | - | - | - | - | - | - | - | - | $0 | VS | |
$AMAT APPLIED MATERIALS INC /DE | 75 | 85 | 87 | 84 | 20.9x | 13.6x | 32.9% | 20.5% | 48.8% | 30.6% | 24.4% | 7.7% | 0.9% | 32.0x | $148.6B | VS | |
$SIMO Silicon Motion Technology CORP | 75 | 84 | 86 | 85 | - | - | - | - | - | - | - | - | - | - | $0 | VS | |
$CODA Coda Octopus Group, Inc. | 74 | 83 | 90 | 79 | 16.3x | 11.9x | 7.4% | 7.5% | 68.3% | 19.5% | 18.2% | 29.0% | 0.0% | 0.0x | $84M | VS | |
$GSK GSK plc | 74 | 84 | 90 | 70 | - | - | - | - | - | - | - | - | - | - | $0 | VS | |
$EFXT Enerflex Ltd. | 74 | 80 | 91 | 83 | - | - | - | - | - | - | - | - | - | - | $0 | VS | |
$BUD Anheuser-Busch InBev SA/NV | 74 | 84 | 97 | 63 | - | - | - | - | - | - | - | - | - | - | $0 | VS | |
$SDGR Schrodinger, Inc. | 35 | 41 | 51 | 17 | - | - | -54.1% | -26.6% | 50.5% | -115.1% | -86.9% | 14.8% | 0.0% | 103.0x | $1.5B | ||
| SECTOR BENCH | - | - | - | - | - | 22.3x | 11.5x | -1.9% | 0.9% | 44.1% | 2.5% | 1.0% | 6.7% | 0.0% | 0.2x | - | REF |
Schrodinger, Inc. (SDGR) receives a "Avoid" rating with a composite score of 35.1/100. It ranks #4098 out of 7,333 stocks in our coverage universe and carries a 1-star rating. Ratings are driven by a 6-factor quantitative model measuring quality, value, momentum, investment, stability, and short interest.
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Lagging peers — losers tend to keep underperforming
Fair valuation relative to peers
Average quality profile
Average volatility — neutral timing signal
Aggressive spending — empire-building risk, dilutive growth
Below-average composite — caution warranted
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Relative valuation derived from Manufacturing sector benchmarks. Model weights: EV/EBITDA (40%), P/B (35%), P/S (25%). Re-calculated daily.
No analyst ratings for SDGR.
View All RatingsROE proxy -54.1% (sector -1.9%)
GM 50% vs sector 44%, OM -115% vs sector 3%
Capital turnover N/A, R&D intensity 78.1%
Rev growth 15%, 6yr history
Interest coverage N/A
Composite assessment of profitability, capital efficiency, and financial strength. Top-tier entities demonstrate sustainable cash flow generation and elite competitive moats.
Profit generated per dollar of shareholder equity
Efficiency of asset utilization
Pricing power and cost efficiency
Core business profitability
Bottom-line profitability
The Quality factor evaluates the persistence and magnitude of realized cash flows. Companies with scores >70 exhibit superior pricing power and structural financial resilience through diverse economic regimes.
Our uncertainty rating tracks the predictability of future cash flows and potential for permanent capital loss. Moderate visibility with standard industry cyclicality.
We rate Schrodinger, Inc. (SDGR) as Avoid with a composite score of 35.1/100 at a current price of $11.38. The stock falls in the bottom quintile, and the multi-factor weakness suggests a high probability of continued underperformance.
Schrodinger, Inc. holds a top-quartile position (#0 of 50) within the Manufacturing sector, based on our composite quantitative scoring across quality, value, momentum, and stability factors. The composite score of 35.1/100 places it at rank #4098 in our full universe.
No Moat
Very High
Poor
Fair Value
Gross margins of 50% signal strong pricing power.
Stable competitive position in a defensive sector.
Leverage of 103% D/E amplifies downside risk.
Weak momentum suggests persistent institutional selling pressure.
Vulnerability to macroeconomic shocks and interest rate volatility.
Schrodinger, Inc. represents a avoid based on multi-factor quantitative performance.
Our quantitative model flags Schrodinger, Inc. with an Avoid rating, assigning a composite score of 35.1/100 and 1 out of 5 stars. Ranked #4098 of 7,333 stocks, SDGR falls in the bottom tier across key factors. Historically, stocks with this profile have faced elevated risk of underperformance and capital loss.
SDGR's quality score of 41/100 is below average, suggesting challenges with profitability or capital efficiency. The company reports a return on equity of -54.1% (sector avg: -1.9%), gross margins of 50.5% (sector avg: 44.1%), net margins of -86.9% (sector avg: 1.0%). Investors should examine whether management is actively addressing these weaknesses or if they reflect structural industry headwinds.
SDGR's value score of 51/100 indicates the stock is fairly valued based on its current fundamentals. Key valuation metrics include a P/B ratio of 2.64x. At this level, neither a clear bargain nor overpriced, the stock's attractiveness depends more on forward growth expectations and qualitative factors.
Schrodinger, Inc.'s investment score of 23/100 suggests limited reinvestment activity. Key growth metrics include revenue growth of 14.8% vs. a sector average of 6.7% and a return on assets of -26.6% (sector: 0.9%). While this can be positive for mature, cash-generative businesses returning capital to shareholders, it may also signal a lack of growth opportunities or management conservatism.
Schrodinger, Inc. is experiencing notably weak momentum with a score of just 17/100. The stock has underperformed its peers and is trending below major moving averages. Revenue growth stands at 14.8% year-over-year, while a beta of 1.31 reflects its sensitivity to broader market moves. While deep momentum weakness can occasionally present value opportunities, it often reflects deteriorating fundamentals or structural headwinds that may persist.
With a stability score of 45/100, SDGR exhibits average financial resilience. Key stability metrics include a beta of 1.31 and a debt-to-equity ratio of 103.00x (sector avg: 0.2x). While the balance sheet is not a major concern, the stock is subject to typical market volatility and may experience sharper drawdowns during risk-off episodes.
Schrodinger, Inc.'s short interest score of 28/100 reveals significant bearish positioning, suggesting institutional investors are actively betting against the stock. Specific risk factors include above-average market sensitivity (beta: 1.31), elevated leverage (D/E: 103.00x), small-cap liquidity risk. At $1.5B (small-cap), SDGR carries meaningful risk and is best suited for investors with high risk tolerance who have thoroughly evaluated the bear thesis.
Schrodinger, Inc. is a small-cap company in the Manufacturing sector, ranked #0 of 50 in its sector (100th percentile) and #4098 of 7,333 overall (44th percentile). Key comparisons include ROE of -54.1% trailing the -1.9% sector median and operating margins of -115.1% below the 2.5% sector average. This top-quartile standing reflects exceptional competitive strength relative to Manufacturing peers.
While SDGR currently exhibits a AVOID profile, superior opportunities exist within the MANUFACTURING sector. Our model identifies several "Strong Buy" candidates with higher quality scores and more attractive valuations among direct industry competitors.
View Top Manufacturing Alpha →Quant Factor Profile
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Improvement in Momentum (17) would have the largest impact on the composite score.
ROE 2748% ABOVE SECTOR MEDIAN (FAVORABLE)
Gross Margin 15% ABOVE SECTOR MEDIAN (FAVORABLE)
Op. Margin 4687% BELOW SECTOR MEDIAN
Above 50MA
37.18%
Net New Highs
+51081
NEW YORK, February 18, 2026--Schrödinger, Inc. (Nasdaq: SDGR) today reported that on February 13, 2026, the company granted (i) non-statutory stock options to purchase 9,600 shares of the company’s common stock to two newly hired employees and (ii) restricted stock units (RSUs) with respect to 18,250 shares of the company’s common stock to eight newly hired employees. These grants were made pursuant to the company’s 2021 Inducement Equity Incentive Plan, were approved by the compensation committ
NEW YORK, February 11, 2026--Schrödinger, Inc. (Nasdaq: SDGR) will report its fourth quarter and full-year 2025 financial results on Wednesday, February 25, 2026, after the financial markets close. The company will host a conference call and webcast at 4:30 p.m. ET.
Unfortunately for some shareholders, the Schrödinger, Inc. ( NASDAQ:SDGR ) share price has dived 26% in the last thirty...
NEW YORK, February 24, 2026--Schrödinger, Inc. (Nasdaq: SDGR) today announced that management will participate in the following conferences in March:
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