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Verdict
Quantitative factor alignment verified for current market regime.
Quant Score
Rank
#4046
Positioning
Market Dominance
Manufacturing
Pharmaceutical Products
$132M
David Hering
Adagio Therapeutics focuses on the discovery, development, and commercialization of antibody-based solutions for infectious diseases in the United States. The company's lead product candidate is the ADG20 (adintrevimab), a neutralizing antibody that is in Phase 3 clinical trials for the treatment and prevention of coronavirus disease.
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| Stock | Rating | Score▼ | Quality | Value | Momentum | P/E | EV/EBITDA | ROE | ROA | Gross Mgn | Op Mgn | Net Mgn | Rev Growth | Div Yield | D/E | Mkt Cap | AUDIT |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
$UL UNILEVER PLC | 78 | 96 | 98 | 59 | - | - | - | - | - | - | - | - | - | - | $0 | VS | |
$ASML ASML HOLDING NV | 77 | 89 | 86 | 83 | - | - | - | - | - | - | - | - | - | - | $0 | VS | |
$ESLT ELBIT SYSTEMS LTD | 76 | 81 | 87 | 85 | - | - | - | - | - | - | - | - | - | - | $0 | VS | |
$MT ArcelorMittal | 75 | 71 | 98 | 85 | - | - | - | - | - | - | - | - | - | - | $0 | VS | |
$AMAT APPLIED MATERIALS INC /DE | 75 | 85 | 87 | 84 | 20.9x | 13.6x | 32.9% | 20.5% | 48.8% | 30.6% | 24.4% | 7.7% | 0.9% | 32.0x | $148.6B | VS | |
$SIMO Silicon Motion Technology CORP | 75 | 84 | 86 | 85 | - | - | - | - | - | - | - | - | - | - | $0 | VS | |
$CODA Coda Octopus Group, Inc. | 74 | 83 | 90 | 79 | 16.3x | 11.9x | 7.4% | 7.5% | 68.3% | 19.5% | 18.2% | 29.0% | 0.0% | 0.0x | $84M | VS | |
$GSK GSK plc | 74 | 84 | 90 | 70 | - | - | - | - | - | - | - | - | - | - | $0 | VS | |
$EFXT Enerflex Ltd. | 74 | 80 | 91 | 83 | - | - | - | - | - | - | - | - | - | - | $0 | VS | |
$BUD Anheuser-Busch InBev SA/NV | 74 | 84 | 97 | 63 | - | - | - | - | - | - | - | - | - | - | $0 | VS | |
$IVVD Invivyd, Inc. | 36 | 38 | 14 | 55 | - | - | -109.8% | -73.4% | 92.0% | -257.9% | -250.3% | 479.9% | 0.0% | 50.0x | $132M | ||
| SECTOR BENCH | - | - | - | - | - | 22.3x | 11.5x | -1.9% | 0.9% | 44.1% | 2.5% | 1.0% | 6.7% | 0.0% | 0.2x | - | REF |
Invivyd, Inc. (IVVD) receives a "Avoid" rating with a composite score of 35.6/100. It ranks #4046 out of 7,333 stocks in our coverage universe and carries a 1-star rating. Ratings are driven by a 6-factor quantitative model measuring quality, value, momentum, investment, stability, and short interest.
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In-line with peers — no strong momentum signal
Expensive relative to fundamentals — limited margin of safety
Average quality profile
High volatility — wider range of outcomes increases timing risk
Aggressive spending — empire-building risk, dilutive growth
Below-average composite — caution warranted
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Relative valuation derived from Manufacturing sector benchmarks. Model weights: EV/EBITDA (40%), P/B (35%), P/S (25%). Re-calculated daily.
No analyst ratings for IVVD.
View All RatingsROE proxy -109.8% (sector -1.9%)
GM 92% vs sector 44%, OM -258% vs sector 3%
Capital turnover N/A, R&D intensity 78.0%
Rev growth 480%, 4yr history
Interest coverage N/A
Composite assessment of profitability, capital efficiency, and financial strength. Top-tier entities demonstrate sustainable cash flow generation and elite competitive moats.
Profit generated per dollar of shareholder equity
Efficiency of asset utilization
Pricing power and cost efficiency
Core business profitability
Bottom-line profitability
The Quality factor evaluates the persistence and magnitude of realized cash flows. Companies with scores >70 exhibit superior pricing power and structural financial resilience through diverse economic regimes.
Our uncertainty rating tracks the predictability of future cash flows and potential for permanent capital loss. Moderate visibility with standard industry cyclicality.
We rate Invivyd, Inc. (IVVD) as Avoid with a composite score of 35.6/100 at a current price of $1.66. The stock falls in the bottom quintile, and the multi-factor weakness suggests a high probability of continued underperformance.
Invivyd, Inc. holds a top-quartile position (#0 of 50) within the Manufacturing sector, based on our composite quantitative scoring across quality, value, momentum, and stability factors. The composite score of 35.6/100 places it at rank #4046 in our full universe.
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High
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Fair Value
Gross margins of 92% signal strong pricing power.
Stable competitive position in a defensive sector.
Vulnerability to macroeconomic shocks and interest rate volatility.
Invivyd, Inc. represents a avoid based on multi-factor quantitative performance.
Our quantitative model flags Invivyd, Inc. with an Avoid rating, assigning a composite score of 35.6/100 and 1 out of 5 stars. Ranked #4046 of 7,333 stocks, IVVD falls in the bottom tier across key factors. Historically, stocks with this profile have faced elevated risk of underperformance and capital loss.
IVVD's quality score of 38/100 is below average, suggesting challenges with profitability or capital efficiency. The company reports a return on equity of -109.8% (sector avg: -1.9%), gross margins of 92.0% (sector avg: 44.1%), net margins of -250.3% (sector avg: 1.0%). Investors should examine whether management is actively addressing these weaknesses or if they reflect structural industry headwinds.
IVVD registers a value score of just 14/100, suggesting the stock trades at a significant premium to its fundamental metrics. Key valuation metrics include a P/B ratio of 4.70x. High-premium valuations like this require strong future execution to avoid multiple compression, and downside risk is elevated if growth disappoints.
Invivyd, Inc.'s investment score of 22/100 suggests limited reinvestment activity. Key growth metrics include revenue growth of 479.9% vs. a sector average of 6.7% and a return on assets of -73.4% (sector: 0.9%). While this can be positive for mature, cash-generative businesses returning capital to shareholders, it may also signal a lack of growth opportunities or management conservatism.
IVVD demonstrates moderate momentum with a score of 55/100, suggesting a neutral price trend without strong directional conviction. Revenue growth stands at 479.9% year-over-year, while a beta of 1.41 reflects its sensitivity to broader market moves. Moderate momentum may indicate the stock is consolidating or transitioning between trends, warranting close monitoring of upcoming catalysts.
IVVD's stability score of 27/100 signals elevated volatility and/or leverage concerns. Key stability metrics include a beta of 1.41 and a debt-to-equity ratio of 50.00x (sector avg: 0.2x). Investors should be prepared for wider-than-average price swings and consider position sizing accordingly to manage portfolio risk.
Invivyd, Inc.'s short interest score of 28/100 reveals significant bearish positioning, suggesting institutional investors are actively betting against the stock. Specific risk factors include above-average market sensitivity (beta: 1.41), elevated leverage (D/E: 50.00x), micro-cap liquidity risk. At $132M (micro-cap), IVVD carries meaningful risk and is best suited for investors with high risk tolerance who have thoroughly evaluated the bear thesis.
Invivyd, Inc. is a micro-cap company in the Manufacturing sector, ranked #0 of 50 in its sector (100th percentile) and #4046 of 7,333 overall (45th percentile). Key comparisons include ROE of -109.8% trailing the -1.9% sector median and operating margins of -257.9% below the 2.5% sector average. This top-quartile standing reflects exceptional competitive strength relative to Manufacturing peers.
While IVVD currently exhibits a AVOID profile, superior opportunities exist within the MANUFACTURING sector. Our model identifies several "Strong Buy" candidates with higher quality scores and more attractive valuations among direct industry competitors.
View Top Manufacturing Alpha →Quant Factor Profile
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Improvement in Value (14) would have the largest impact on the composite score.
ROE 5677% ABOVE SECTOR MEDIAN (FAVORABLE)
Gross Margin 109% ABOVE SECTOR MEDIAN (FAVORABLE)
Op. Margin 10373% BELOW SECTOR MEDIAN
The Invivyd, Inc. ( NASDAQ:IVVD ) share price has softened a substantial 26% over the previous 30 days, handing back...

Biotech firm Invivyd reported Q2 2025 earnings with 413% revenue growth to $11.8 million, falling short of analyst expectations. The company continues developing COVID-19 monoclonal antibodies while exploring new viral disease treatments.
“A Statistical Immune Correlates of Protection Model for Predicting Efficacy from Neutralizing Antibody Titers to Establish Immunobridging of Monoclonal Antibodies for Prevention of COVID-19” was published in Infectious Diseases and Therapy This peer-reviewed analysis describes the relationship between anti-COVID monoclonal antibody (mAb) levels in patient serum and demonstrated clinical protection from multiple Omicron-virus variants in a modern, COVID-endemic, seropositive population, adding t
Halozyme Therapeutics (HALO) delivered earnings and revenue surprises of -111.16% and +0.70%, respectively, for the quarter ended December 2025. Do the numbers hold clues to what lies ahead for the stock?

Invivyd reported Q4 2025 PEMGARDA net product revenue of $17.2 million, representing 25% year-over-year growth and 31% quarter-over-quarter growth. The company announced a strong balance sheet with $226.7 million in cash after raising over $200 million in 2H 2025. Key developments include initiation of the DECLARATION Phase 3 pivotal trial for COVID vaccine-alternative VYD2311 with top-line data expected mid-2026, FDA Fast Track designation for VYD2311, and nomination of potential best-in-class RSV antibody VBY329 for preclinical development.
Above 50MA
37.18%
Net New Highs
+51081